Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables
Abstract. Purpose: To examine the age and sex‐specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables. Methods: We carried out a population‐based study using a random sample taken from the national population census for citizens of Reykjavik,...
Published in: | Acta Ophthalmologica Scandinavica |
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crwiley:10.1111/j.1600-0420.2007.01051.x 2024-09-30T14:37:28+00:00 Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables Arnarsson, Arsaell Damji, Karim F. Sverrisson, Thordur Sasaki, Hiroshi Jonasson, Fridbert 2007 http://dx.doi.org/10.1111/j.1600-0420.2007.01051.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1600-0420.2007.01051.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1600-0420.2007.01051.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Acta Ophthalmologica Scandinavica volume 85, issue 8, page 822-827 ISSN 1395-3907 1600-0420 journal-article 2007 crwiley https://doi.org/10.1111/j.1600-0420.2007.01051.x 2024-09-03T04:22:30Z Abstract. Purpose: To examine the age and sex‐specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables. Methods: We carried out a population‐based study using a random sample taken from the national population census for citizens of Reykjavik, aged ≥ 50 years. A total of 1045 individuals participated in all parts of the study. Pseudoexfoliation was established by slit‐lamp examination with a maximally dilated pupil carried out by two experienced ophthalmologists, who were masked to one another’s results except in cases of disagreement where they had to reach a consensus. Results: In all, 108 (10.7%) persons were found to have PEX in at least one eye. Prevalence increased from 2.5% in those aged 50–59 years to 40.6% in those aged ≥ 80 years. Women were more frequently affected than men (12.3% versus 8.7%). This difference remained statistically significant after controlling for the effect of age (p < 0.001). Eyes with PEX were found to have higher intraocular pressure (IOP) than eyes without PEX (p < 0.05). However, PEX was not found to be related to central corneal thickness, anterior chamber depth, lens thickness, nuclear lens opacifications or optic disc morphology in a multivariate model. Conclusions: Pseudoexfoliation is an age‐related phenomenon commonly found in Iceland. It is more commonly found in women than in men and is associated with elevated IOP. Article in Journal/Newspaper Iceland Wiley Online Library Acta Ophthalmologica Scandinavica 85 8 822 827 |
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English |
description |
Abstract. Purpose: To examine the age and sex‐specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables. Methods: We carried out a population‐based study using a random sample taken from the national population census for citizens of Reykjavik, aged ≥ 50 years. A total of 1045 individuals participated in all parts of the study. Pseudoexfoliation was established by slit‐lamp examination with a maximally dilated pupil carried out by two experienced ophthalmologists, who were masked to one another’s results except in cases of disagreement where they had to reach a consensus. Results: In all, 108 (10.7%) persons were found to have PEX in at least one eye. Prevalence increased from 2.5% in those aged 50–59 years to 40.6% in those aged ≥ 80 years. Women were more frequently affected than men (12.3% versus 8.7%). This difference remained statistically significant after controlling for the effect of age (p < 0.001). Eyes with PEX were found to have higher intraocular pressure (IOP) than eyes without PEX (p < 0.05). However, PEX was not found to be related to central corneal thickness, anterior chamber depth, lens thickness, nuclear lens opacifications or optic disc morphology in a multivariate model. Conclusions: Pseudoexfoliation is an age‐related phenomenon commonly found in Iceland. It is more commonly found in women than in men and is associated with elevated IOP. |
format |
Article in Journal/Newspaper |
author |
Arnarsson, Arsaell Damji, Karim F. Sverrisson, Thordur Sasaki, Hiroshi Jonasson, Fridbert |
spellingShingle |
Arnarsson, Arsaell Damji, Karim F. Sverrisson, Thordur Sasaki, Hiroshi Jonasson, Fridbert Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables |
author_facet |
Arnarsson, Arsaell Damji, Karim F. Sverrisson, Thordur Sasaki, Hiroshi Jonasson, Fridbert |
author_sort |
Arnarsson, Arsaell |
title |
Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables |
title_short |
Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables |
title_full |
Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables |
title_fullStr |
Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables |
title_full_unstemmed |
Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables |
title_sort |
pseudoexfoliation in the reykjavik eye study: prevalence and related ophthalmological variables |
publisher |
Wiley |
publishDate |
2007 |
url |
http://dx.doi.org/10.1111/j.1600-0420.2007.01051.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1600-0420.2007.01051.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1600-0420.2007.01051.x |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Acta Ophthalmologica Scandinavica volume 85, issue 8, page 822-827 ISSN 1395-3907 1600-0420 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1600-0420.2007.01051.x |
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Acta Ophthalmologica Scandinavica |
container_volume |
85 |
container_issue |
8 |
container_start_page |
822 |
op_container_end_page |
827 |
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1811640312909529088 |