An Immune Response to Ice Crystals in North Atlantic Fishes
In mammals, the presence of crystals composed of small organic molecules, including urate and related compounds, has been shown to trigger an inflammatory response and the subsequent production of specific immunoglobulins (Ig's). Many fishes that are exposed to ice crystals in cold temperate an...
Published in: | European Journal of Biochemistry |
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Language: | English |
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crwiley:10.1111/j.1432-1033.1996.00740.x 2024-06-02T08:11:21+00:00 An Immune Response to Ice Crystals in North Atlantic Fishes Verdier, Jean‐Michel Ewart, K. Vanya Griffith, Marilyn Hew, Choy L. 1996 http://dx.doi.org/10.1111/j.1432-1033.1996.00740.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1432-1033.1996.00740.x https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1432-1033.1996.00740.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor European Journal of Biochemistry volume 241, issue 3, page 740-743 ISSN 0014-2956 1432-1033 journal-article 1996 crwiley https://doi.org/10.1111/j.1432-1033.1996.00740.x 2024-05-03T11:21:46Z In mammals, the presence of crystals composed of small organic molecules, including urate and related compounds, has been shown to trigger an inflammatory response and the subsequent production of specific immunoglobulins (Ig's). Many fishes that are exposed to ice crystals in cold temperate and polar oceans may harbour ice crystals internally. Here, we report evidence for a specific immune response to ice crystals in cold‐ocean marine fishes. Using ice nucleation activity as an assay, anti‐ice Ig's were detected in the sera of the cold‐ocean marine fish species, ocean pout ( Macrozoarces americanus ) and Atlantic herring ( Clupea harengus harengus ), but not in the sera of species that are not exposed to ice. Purified Ig's isolated from ocean pout serum using two different protocols showed ice nucleation activity, thus demonstrating the presence of ice binding specificity among these Ig's. Article in Journal/Newspaper North Atlantic Wiley Online Library European Journal of Biochemistry 241 3 740 743 |
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Open Polar |
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Wiley Online Library |
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crwiley |
language |
English |
description |
In mammals, the presence of crystals composed of small organic molecules, including urate and related compounds, has been shown to trigger an inflammatory response and the subsequent production of specific immunoglobulins (Ig's). Many fishes that are exposed to ice crystals in cold temperate and polar oceans may harbour ice crystals internally. Here, we report evidence for a specific immune response to ice crystals in cold‐ocean marine fishes. Using ice nucleation activity as an assay, anti‐ice Ig's were detected in the sera of the cold‐ocean marine fish species, ocean pout ( Macrozoarces americanus ) and Atlantic herring ( Clupea harengus harengus ), but not in the sera of species that are not exposed to ice. Purified Ig's isolated from ocean pout serum using two different protocols showed ice nucleation activity, thus demonstrating the presence of ice binding specificity among these Ig's. |
format |
Article in Journal/Newspaper |
author |
Verdier, Jean‐Michel Ewart, K. Vanya Griffith, Marilyn Hew, Choy L. |
spellingShingle |
Verdier, Jean‐Michel Ewart, K. Vanya Griffith, Marilyn Hew, Choy L. An Immune Response to Ice Crystals in North Atlantic Fishes |
author_facet |
Verdier, Jean‐Michel Ewart, K. Vanya Griffith, Marilyn Hew, Choy L. |
author_sort |
Verdier, Jean‐Michel |
title |
An Immune Response to Ice Crystals in North Atlantic Fishes |
title_short |
An Immune Response to Ice Crystals in North Atlantic Fishes |
title_full |
An Immune Response to Ice Crystals in North Atlantic Fishes |
title_fullStr |
An Immune Response to Ice Crystals in North Atlantic Fishes |
title_full_unstemmed |
An Immune Response to Ice Crystals in North Atlantic Fishes |
title_sort |
immune response to ice crystals in north atlantic fishes |
publisher |
Wiley |
publishDate |
1996 |
url |
http://dx.doi.org/10.1111/j.1432-1033.1996.00740.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1432-1033.1996.00740.x https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1432-1033.1996.00740.x |
genre |
North Atlantic |
genre_facet |
North Atlantic |
op_source |
European Journal of Biochemistry volume 241, issue 3, page 740-743 ISSN 0014-2956 1432-1033 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1432-1033.1996.00740.x |
container_title |
European Journal of Biochemistry |
container_volume |
241 |
container_issue |
3 |
container_start_page |
740 |
op_container_end_page |
743 |
_version_ |
1800757458215370752 |