Population studies of the human VK A18 gene polymorphism in Caucasians, blacks and Eskimos

• Published in: Tissue Antigens
• Main Authors: Juul, L., Hougs, L., Andersen, V., Garred, P., Ryder, L., Svejgaard, A., Høgh, B., Lamm, L., Graugaard, B., Barington, T.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1997
• Subjects: Atkinson; Greenland; eskimo*
• Online Access: http://dx.doi.org/10.1111/j.1399-0039.1997.tb02807.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1399-0039.1997.tb02807.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1399-0039.1997.tb02807.x

Immunoglobulin gene polymorphisms are interesting because they reflect differences in the available antibody repertoire which may affect the susceptibility to specific infections. Until recently, the human Vk gene, A18, was known as a nonfunctional gene only. In this study, we cloned and sequenced f...