HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland
HLA‐A, B and C antigens were determined from 63 cases of juvenile‐onset, insulin‐dependent diabetes mellitus (IDDM) in northern Finland. There was a very strong association between IDDM and HLA‐B8 and B15 antigens in this area where the incidence of IDDM is also high. Relative risks for B8 and B15 w...
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crwiley:10.1111/j.1399-0039.1980.tb00199.x 2024-06-02T08:11:59+00:00 HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland Ilonen, J. Herva, E. Tiilikainen, A. Åkerblom, H. K. Mustonen, A. Koivukangas, T. Kouvalainen, K. 1980 http://dx.doi.org/10.1111/j.1399-0039.1980.tb00199.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1399-0039.1980.tb00199.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1399-0039.1980.tb00199.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Tissue Antigens volume 15, issue 4, page 381-388 ISSN 0001-2815 1399-0039 journal-article 1980 crwiley https://doi.org/10.1111/j.1399-0039.1980.tb00199.x 2024-05-03T10:40:22Z HLA‐A, B and C antigens were determined from 63 cases of juvenile‐onset, insulin‐dependent diabetes mellitus (IDDM) in northern Finland. There was a very strong association between IDDM and HLA‐B8 and B15 antigens in this area where the incidence of IDDM is also high. Relative risks for B8 and B15 were 4.8 and 3.8, respectively. In a small group of subjects typed for HLA‐D antigens Dw3 and Dw4 appeared to be stronger risk factors than associated B antigens, whereas Dw2 was almost totally absent in the patients. Article in Journal/Newspaper Northern Finland Wiley Online Library Tissue Antigens 15 4 381 388 |
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Wiley Online Library |
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crwiley |
language |
English |
description |
HLA‐A, B and C antigens were determined from 63 cases of juvenile‐onset, insulin‐dependent diabetes mellitus (IDDM) in northern Finland. There was a very strong association between IDDM and HLA‐B8 and B15 antigens in this area where the incidence of IDDM is also high. Relative risks for B8 and B15 were 4.8 and 3.8, respectively. In a small group of subjects typed for HLA‐D antigens Dw3 and Dw4 appeared to be stronger risk factors than associated B antigens, whereas Dw2 was almost totally absent in the patients. |
format |
Article in Journal/Newspaper |
author |
Ilonen, J. Herva, E. Tiilikainen, A. Åkerblom, H. K. Mustonen, A. Koivukangas, T. Kouvalainen, K. |
spellingShingle |
Ilonen, J. Herva, E. Tiilikainen, A. Åkerblom, H. K. Mustonen, A. Koivukangas, T. Kouvalainen, K. HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland |
author_facet |
Ilonen, J. Herva, E. Tiilikainen, A. Åkerblom, H. K. Mustonen, A. Koivukangas, T. Kouvalainen, K. |
author_sort |
Ilonen, J. |
title |
HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland |
title_short |
HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland |
title_full |
HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland |
title_fullStr |
HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland |
title_full_unstemmed |
HLA Genetics of Insulin‐Dependent Juvenile‐Onset Diabetes Mellitus in Northern Finland |
title_sort |
hla genetics of insulin‐dependent juvenile‐onset diabetes mellitus in northern finland |
publisher |
Wiley |
publishDate |
1980 |
url |
http://dx.doi.org/10.1111/j.1399-0039.1980.tb00199.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1399-0039.1980.tb00199.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1399-0039.1980.tb00199.x |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
Tissue Antigens volume 15, issue 4, page 381-388 ISSN 0001-2815 1399-0039 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1399-0039.1980.tb00199.x |
container_title |
Tissue Antigens |
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15 |
container_issue |
4 |
container_start_page |
381 |
op_container_end_page |
388 |
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1800758297559564288 |