Major histocompatibility complex variation at three class II loci in the northern elephant seal
Abstract Northern elephant seals were hunted to near extinction in the 19th century, yet have recovered remarkably and now number around 175 000. We surveyed 110 seals for single‐strand conformation polymorphism (SSCP) and sequence variation at three major histocompatibility (MHC) class II loci ( DQ...
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crwiley:10.1111/j.1365-294x.2004.02095.x 2024-06-23T07:52:28+00:00 Major histocompatibility complex variation at three class II loci in the northern elephant seal Weber, Diana S. Stewart, Brent S. Schienman, John Lehman, Niles 2004 http://dx.doi.org/10.1111/j.1365-294x.2004.02095.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-294X.2004.02095.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-294X.2004.02095.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Molecular Ecology volume 13, issue 3, page 711-718 ISSN 0962-1083 1365-294X journal-article 2004 crwiley https://doi.org/10.1111/j.1365-294x.2004.02095.x 2024-05-31T08:09:43Z Abstract Northern elephant seals were hunted to near extinction in the 19th century, yet have recovered remarkably and now number around 175 000. We surveyed 110 seals for single‐strand conformation polymorphism (SSCP) and sequence variation at three major histocompatibility (MHC) class II loci ( DQA , DQB and DRB ) to evaluate the genetic consequences of the population bottleneck at these loci vs. other well‐studied genes. We found very few alleles at each MHC locus, significant variation among breeding sites for the DQA locus, and linkage disequilibrium between the DQB and DRB loci. Northern elephant seals are evidently inbred, although there is as yet no evidence of correlative reductions in fitness. Article in Journal/Newspaper Elephant Seal Elephant Seals Wiley Online Library Molecular Ecology 13 3 711 718 |
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Open Polar |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract Northern elephant seals were hunted to near extinction in the 19th century, yet have recovered remarkably and now number around 175 000. We surveyed 110 seals for single‐strand conformation polymorphism (SSCP) and sequence variation at three major histocompatibility (MHC) class II loci ( DQA , DQB and DRB ) to evaluate the genetic consequences of the population bottleneck at these loci vs. other well‐studied genes. We found very few alleles at each MHC locus, significant variation among breeding sites for the DQA locus, and linkage disequilibrium between the DQB and DRB loci. Northern elephant seals are evidently inbred, although there is as yet no evidence of correlative reductions in fitness. |
format |
Article in Journal/Newspaper |
author |
Weber, Diana S. Stewart, Brent S. Schienman, John Lehman, Niles |
spellingShingle |
Weber, Diana S. Stewart, Brent S. Schienman, John Lehman, Niles Major histocompatibility complex variation at three class II loci in the northern elephant seal |
author_facet |
Weber, Diana S. Stewart, Brent S. Schienman, John Lehman, Niles |
author_sort |
Weber, Diana S. |
title |
Major histocompatibility complex variation at three class II loci in the northern elephant seal |
title_short |
Major histocompatibility complex variation at three class II loci in the northern elephant seal |
title_full |
Major histocompatibility complex variation at three class II loci in the northern elephant seal |
title_fullStr |
Major histocompatibility complex variation at three class II loci in the northern elephant seal |
title_full_unstemmed |
Major histocompatibility complex variation at three class II loci in the northern elephant seal |
title_sort |
major histocompatibility complex variation at three class ii loci in the northern elephant seal |
publisher |
Wiley |
publishDate |
2004 |
url |
http://dx.doi.org/10.1111/j.1365-294x.2004.02095.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-294X.2004.02095.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-294X.2004.02095.x |
genre |
Elephant Seal Elephant Seals |
genre_facet |
Elephant Seal Elephant Seals |
op_source |
Molecular Ecology volume 13, issue 3, page 711-718 ISSN 0962-1083 1365-294X |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1365-294x.2004.02095.x |
container_title |
Molecular Ecology |
container_volume |
13 |
container_issue |
3 |
container_start_page |
711 |
op_container_end_page |
718 |
_version_ |
1802643774326702080 |