Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica
Abstract Susceptibility and antibody production against pathogenic and vaccine strains of the haemoflagellate, Cryptobia salmositica were investigated in five full‐sib families (A–E) of Atlantic salmon, Salmo salar . Humoral response and susceptibility of families were compared within three treatmen...
Published in: | Journal of Fish Diseases |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2004
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1111/j.1365-2761.2004.00568.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.2004.00568.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.2004.00568.x |
id |
crwiley:10.1111/j.1365-2761.2004.00568.x |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1111/j.1365-2761.2004.00568.x 2024-06-02T08:03:34+00:00 Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica Chin, A Glebe, B D Woo, P T K 2004 http://dx.doi.org/10.1111/j.1365-2761.2004.00568.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.2004.00568.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.2004.00568.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Fish Diseases volume 27, issue 8, page 471-481 ISSN 0140-7775 1365-2761 journal-article 2004 crwiley https://doi.org/10.1111/j.1365-2761.2004.00568.x 2024-05-03T10:39:53Z Abstract Susceptibility and antibody production against pathogenic and vaccine strains of the haemoflagellate, Cryptobia salmositica were investigated in five full‐sib families (A–E) of Atlantic salmon, Salmo salar . Humoral response and susceptibility of families were compared within three treatments: infection, vaccination and vaccination followed by challenge. Parasitaemias caused by the vaccine strain of C. salmositica were considerably lower than those caused by the pathogenic strain. All vaccinated families were protected when challenged with the pathogenic strain. Family B had significantly lower parasitaemias (with both strains) than the other families. When naïve fish were infected with the pathogenic strain, this family had a significantly lower and earlier peak parasitaemia (4.3 ±1.3 × 10 6 parasites mL −1 blood at 3 weeks post‐infection; w.p.i.) than the other families. Family C had the highest peak (11.1 ± 1.2 × 10 6 parasites mL −1 blood), which occurred at 4 w.p.i. Antibodies against C. salmositica were detected earlier in Family B (3 w.p.i.) than in Family C (5 w.p.i.). This demonstrates an association of increased susceptibility with a delayed antibody response. Western immunoblot identified antibodies against 112, 181 and 200 kDa antigens earlier in more resistant fish (Family B). Antigenic stimulation leading to a stronger antibody response was shown with the vaccine strain and in the later stages of infection. Article in Journal/Newspaper Atlantic salmon Salmo salar Wiley Online Library Journal of Fish Diseases 27 8 471 481 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Abstract Susceptibility and antibody production against pathogenic and vaccine strains of the haemoflagellate, Cryptobia salmositica were investigated in five full‐sib families (A–E) of Atlantic salmon, Salmo salar . Humoral response and susceptibility of families were compared within three treatments: infection, vaccination and vaccination followed by challenge. Parasitaemias caused by the vaccine strain of C. salmositica were considerably lower than those caused by the pathogenic strain. All vaccinated families were protected when challenged with the pathogenic strain. Family B had significantly lower parasitaemias (with both strains) than the other families. When naïve fish were infected with the pathogenic strain, this family had a significantly lower and earlier peak parasitaemia (4.3 ±1.3 × 10 6 parasites mL −1 blood at 3 weeks post‐infection; w.p.i.) than the other families. Family C had the highest peak (11.1 ± 1.2 × 10 6 parasites mL −1 blood), which occurred at 4 w.p.i. Antibodies against C. salmositica were detected earlier in Family B (3 w.p.i.) than in Family C (5 w.p.i.). This demonstrates an association of increased susceptibility with a delayed antibody response. Western immunoblot identified antibodies against 112, 181 and 200 kDa antigens earlier in more resistant fish (Family B). Antigenic stimulation leading to a stronger antibody response was shown with the vaccine strain and in the later stages of infection. |
format |
Article in Journal/Newspaper |
author |
Chin, A Glebe, B D Woo, P T K |
spellingShingle |
Chin, A Glebe, B D Woo, P T K Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica |
author_facet |
Chin, A Glebe, B D Woo, P T K |
author_sort |
Chin, A |
title |
Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica |
title_short |
Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica |
title_full |
Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica |
title_fullStr |
Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica |
title_full_unstemmed |
Humoral response and susceptibility of five full‐sib families of Atlantic salmon, Salmo salar L., to the haemoflagellate, Cryptobia salmositica |
title_sort |
humoral response and susceptibility of five full‐sib families of atlantic salmon, salmo salar l., to the haemoflagellate, cryptobia salmositica |
publisher |
Wiley |
publishDate |
2004 |
url |
http://dx.doi.org/10.1111/j.1365-2761.2004.00568.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.2004.00568.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.2004.00568.x |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Journal of Fish Diseases volume 27, issue 8, page 471-481 ISSN 0140-7775 1365-2761 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1365-2761.2004.00568.x |
container_title |
Journal of Fish Diseases |
container_volume |
27 |
container_issue |
8 |
container_start_page |
471 |
op_container_end_page |
481 |
_version_ |
1800748137885728768 |