Effects of potassium aluminium sulphate (alum) used in an Aeromonas salmonicida bacterin on Atlantic salmon, Salmo salar L.

• Published in: Journal of Fish Diseases
• Main Authors: MULVEY, B., LANDOLT, M. L., BUSCH, R. A.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1995
• Subjects: Atlantic salmon; Salmo salar
• Online Access: http://dx.doi.org/10.1111/j.1365-2761.1995.tb00353.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1995.tb00353.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1995.tb00353.x

Abstract. Potassium aluminium sulphate (alum) was tested for use as an adjuvant in an Aeromonas salmonicida bacterin injected into Atlantic salmon, Salmo salar L. Potential side‐effects of visceral adhesions, diminished growth and toxicity, as well as adjuvant effects, were examined. Both alum and the bacterin alone induced inflammation and adhesion formation when injected into the peritoneal cavity. When bacterin and alum were combined, these effects were compounded. Growth was not affected by any of the injected treatments. The acute toxicity of the bacterin was reduced from 33.7 to 0.3% mortality by the addition of alum. Alum appeared to enhance protection against challenge, but there were no statistically significant differences in protection between injecting bacterin alone or injecting bacterin with alum.