Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial
Abstract. The incorporation of the quinolone antibacterials oxolinic acid and sarafloxacin into Artemia fransciscana and subsequently into turbot, Scophthalmus maximus (L.), was quantified, and the therapeutic efficacy of the bioencapsulated drugs against challenge with Vibrio anguillarum 8587 was i...
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Language: | English |
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Wiley
1995
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Online Access: | http://dx.doi.org/10.1111/j.1365-2761.1995.tb00298.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1995.tb00298.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1995.tb00298.x |
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crwiley:10.1111/j.1365-2761.1995.tb00298.x 2024-06-02T08:14:10+00:00 Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial DUIS, K. HAMMER, C. BEVERIDGE, M. C. M. INGLIS, V. BRAUM, E. 1995 http://dx.doi.org/10.1111/j.1365-2761.1995.tb00298.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1995.tb00298.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1995.tb00298.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Fish Diseases volume 18, issue 3, page 229-238 ISSN 0140-7775 1365-2761 journal-article 1995 crwiley https://doi.org/10.1111/j.1365-2761.1995.tb00298.x 2024-05-03T10:49:27Z Abstract. The incorporation of the quinolone antibacterials oxolinic acid and sarafloxacin into Artemia fransciscana and subsequently into turbot, Scophthalmus maximus (L.), was quantified, and the therapeutic efficacy of the bioencapsulated drugs against challenge with Vibrio anguillarum 8587 was investigated. Five‐week‐old turbot were fed for 10 days with Artemia enriched with either oxolinic acid or sarafloxacin. Therapeutic concentrations were reached with both drugs (11.8 μg oxolinic acid per gram fresh weight: 1.8 μg sarafloxacin per gram fresh weight). Both treatments proved effective against challenge, with V. anguillarum ‐specific mortality rates of 6 and 14% in the oxolinic acid and sarafloxacin treated groups, respectively, compared with 75% in the infected control. However, incorporation of the drug by brine shrimp was extremely low (<1%), and therefore, bioencapsulation cannot be considered as an appropriate method to reduce impact on the environment. Article in Journal/Newspaper Scophthalmus maximus Turbot Wiley Online Library Journal of Fish Diseases 18 3 229 238 |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract. The incorporation of the quinolone antibacterials oxolinic acid and sarafloxacin into Artemia fransciscana and subsequently into turbot, Scophthalmus maximus (L.), was quantified, and the therapeutic efficacy of the bioencapsulated drugs against challenge with Vibrio anguillarum 8587 was investigated. Five‐week‐old turbot were fed for 10 days with Artemia enriched with either oxolinic acid or sarafloxacin. Therapeutic concentrations were reached with both drugs (11.8 μg oxolinic acid per gram fresh weight: 1.8 μg sarafloxacin per gram fresh weight). Both treatments proved effective against challenge, with V. anguillarum ‐specific mortality rates of 6 and 14% in the oxolinic acid and sarafloxacin treated groups, respectively, compared with 75% in the infected control. However, incorporation of the drug by brine shrimp was extremely low (<1%), and therefore, bioencapsulation cannot be considered as an appropriate method to reduce impact on the environment. |
format |
Article in Journal/Newspaper |
author |
DUIS, K. HAMMER, C. BEVERIDGE, M. C. M. INGLIS, V. BRAUM, E. |
spellingShingle |
DUIS, K. HAMMER, C. BEVERIDGE, M. C. M. INGLIS, V. BRAUM, E. Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial |
author_facet |
DUIS, K. HAMMER, C. BEVERIDGE, M. C. M. INGLIS, V. BRAUM, E. |
author_sort |
DUIS, K. |
title |
Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial |
title_short |
Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial |
title_full |
Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial |
title_fullStr |
Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial |
title_full_unstemmed |
Delivery of quinolone antibacterials to turbot, Scophthalmus maximus (L.), via bioencapsulation: quantification and efficacy trial |
title_sort |
delivery of quinolone antibacterials to turbot, scophthalmus maximus (l.), via bioencapsulation: quantification and efficacy trial |
publisher |
Wiley |
publishDate |
1995 |
url |
http://dx.doi.org/10.1111/j.1365-2761.1995.tb00298.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1995.tb00298.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1995.tb00298.x |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_source |
Journal of Fish Diseases volume 18, issue 3, page 229-238 ISSN 0140-7775 1365-2761 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1365-2761.1995.tb00298.x |
container_title |
Journal of Fish Diseases |
container_volume |
18 |
container_issue |
3 |
container_start_page |
229 |
op_container_end_page |
238 |
_version_ |
1800737886940692480 |