Antigenic analysis of Norwegian aquatic birnavirus isolates using monoclonal antibodies—with special reference to fish species, age and health status

• Published in: Journal of Fish Diseases
• Main Authors: MELBY, H. P., CASWELL‐RENO, P., FALK, K.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1994
• Subjects: Norway; Atlantic salmon; Salmo salar
• Online Access: http://dx.doi.org/10.1111/j.1365-2761.1994.tb00348.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1994.tb00348.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1994.tb00348.x

Abstract. A panel of 11 monoclonal antibodies (MAbs) was used in an immunodot assay to investigate the antigenic relationship of a representative selection of aquatic biroaviruses isolated in Norway from different species of both carrier and diseased fish. All the 81 isolates shared a serogroup A‐speeifie epitopc, and 67 of them had a reaction pattern identical to the Sp‐type strain. Of the other 14 isolates, nine resembled the Sp‐type strain, two resembled both the Sp‐ and He‐type strains, two were closest to the Ab‐type strain and one resembled the Te‐type strain. Sp‐related strains were predominant from all nine host groups, including from both Atlantic salmon, Salmo salar L., with infectious pancreatic necrosis (IPN) and healthy. Atlantic salmon. The N1 strain reacted identically to the Sp‐type strain.