Do extracellular products of Aeromonas salmonicida induce thrombosis by entering the fish coagulation system at factor X?

• Published in: Journal of Fish Diseases
• Main Authors: SALTE, R., NORBERG, K., ØDEGAARD, O. R.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1991
• Subjects: Atlantic salmon
• Online Access: http://dx.doi.org/10.1111/j.1365-2761.1991.tb00839.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1991.tb00839.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1991.tb00839.x

Abstract. Thrombosis of minute vessels is a common feature of acute furunculosis in Atlantic salmon. Crude extracellular products (F.CP) of Aeromans, salmonicida injected into the dorsal aorta of cannulated fish elicited an activation of the coagulations systems of the fish When screened with a number of chromogenic substrates, the ECP protease revealed a factor‐X like activity. Thus, it may he hypothesized that the ECP induces thrombosis by entering the fish coagulation systems at factor X. and that thrombus formation is a way of creating a site of infection.