Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees
Genetic diversity in the second domain exon of Atlantic salmon ( Salmo salar ) major histocompatibility complex (Mhc) class I was investigated in two dams and nine of their haploid offspring by means of polymerase chain reaction (PCR) and DNA sequence analysis. A similar study was also performed on...
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Language: | English |
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1997
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Online Access: | http://dx.doi.org/10.1111/j.1365-2052.1997.00183.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2052.1997.00183.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2052.1997.00183.x |
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crwiley:10.1111/j.1365-2052.1997.00183.x 2024-06-02T08:03:27+00:00 Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees Grimholt, U Olsaker, I Lingaas, F Lie, Ø 1997 http://dx.doi.org/10.1111/j.1365-2052.1997.00183.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2052.1997.00183.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2052.1997.00183.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Animal Genetics volume 28, issue 6, page 385-390 ISSN 0268-9146 1365-2052 journal-article 1997 crwiley https://doi.org/10.1111/j.1365-2052.1997.00183.x 2024-05-03T10:44:59Z Genetic diversity in the second domain exon of Atlantic salmon ( Salmo salar ) major histocompatibility complex (Mhc) class I was investigated in two dams and nine of their haploid offspring by means of polymerase chain reaction (PCR) and DNA sequence analysis. A similar study was also performed on nine diploid offspring from one of these dams. The complex segregation patterns and sequence similarities between variants make definitive allele, haplotype and locus assignments difficult. There are, however, indications of six Mhc‐ Sasa class I loci and a fairly well‐defined haplotype of four variants. One non‐polymorphic variant present in most specimens could be a salmon analogue to the human non‐classical loci. Article in Journal/Newspaper Atlantic salmon Salmo salar Wiley Online Library Animal Genetics 28 6 385 390 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Genetic diversity in the second domain exon of Atlantic salmon ( Salmo salar ) major histocompatibility complex (Mhc) class I was investigated in two dams and nine of their haploid offspring by means of polymerase chain reaction (PCR) and DNA sequence analysis. A similar study was also performed on nine diploid offspring from one of these dams. The complex segregation patterns and sequence similarities between variants make definitive allele, haplotype and locus assignments difficult. There are, however, indications of six Mhc‐ Sasa class I loci and a fairly well‐defined haplotype of four variants. One non‐polymorphic variant present in most specimens could be a salmon analogue to the human non‐classical loci. |
format |
Article in Journal/Newspaper |
author |
Grimholt, U Olsaker, I Lingaas, F Lie, Ø |
spellingShingle |
Grimholt, U Olsaker, I Lingaas, F Lie, Ø Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees |
author_facet |
Grimholt, U Olsaker, I Lingaas, F Lie, Ø |
author_sort |
Grimholt, U |
title |
Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees |
title_short |
Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees |
title_full |
Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees |
title_fullStr |
Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees |
title_full_unstemmed |
Sequence analysis of MHC class I α2 domain exon variants in one diploid and two haploid Atlantic salmon pedigrees |
title_sort |
sequence analysis of mhc class i α2 domain exon variants in one diploid and two haploid atlantic salmon pedigrees |
publisher |
Wiley |
publishDate |
1997 |
url |
http://dx.doi.org/10.1111/j.1365-2052.1997.00183.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2052.1997.00183.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2052.1997.00183.x |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Animal Genetics volume 28, issue 6, page 385-390 ISSN 0268-9146 1365-2052 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1365-2052.1997.00183.x |
container_title |
Animal Genetics |
container_volume |
28 |
container_issue |
6 |
container_start_page |
385 |
op_container_end_page |
390 |
_version_ |
1800747964511027200 |