Molecular Epidemiology of Rabies in Thailand
Abstract For the purpose of making clear the dynamics of rabies viruses that are prevalent among dogs in Asia, especially Thailand, nucleoprotein (N) genes of isolates derived from Thailand were partially sequenced, and a phylogenetic analysis was performed on the basis of the sequencing data. First...
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crwiley:10.1111/j.1348-0421.1999.tb02441.x 2024-09-09T19:25:11+00:00 Molecular Epidemiology of Rabies in Thailand Ito, Naoto Sugiyama, Makoto Oraveerakul, Kanisak Piyaviriyakul, Prapruddee Lumlertdacha, Boonlert Arai, Yoko T. Tamura, Yutaka Mori, Yoshio Minamoto, Nobuyuki 1999 http://dx.doi.org/10.1111/j.1348-0421.1999.tb02441.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1348-0421.1999.tb02441.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1348-0421.1999.tb02441.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Microbiology and Immunology volume 43, issue 6, page 551-559 ISSN 0385-5600 1348-0421 journal-article 1999 crwiley https://doi.org/10.1111/j.1348-0421.1999.tb02441.x 2024-08-09T04:28:06Z Abstract For the purpose of making clear the dynamics of rabies viruses that are prevalent among dogs in Asia, especially Thailand, nucleoprotein (N) genes of isolates derived from Thailand were partially sequenced, and a phylogenetic analysis was performed on the basis of the sequencing data. Firstly, all 27 isolates from Thailand belonged to one group that was distantly related to an isolate from China and was separated into at least six lineages. On the other hand, the isolate from Japan was related to viruses from the Arctic. Secondly, in order to analyze the diversity of the N gene more conveniently, restriction fragment length polymorphism (RFLP) analysis was performed on the N gene of 27 isolates from Thailand. The RFLP analysis could distinguish the lineages of each isolate, and the lineages of additional 34 isolates were deduced by this method. On examination of the geographical distribution of the six lineages, based on the results of phylogenetic and RFLP analyses, it was clear that infection cycles of the rabies virus in Thailand have tended to be maintained endemically. Article in Journal/Newspaper Arctic Wiley Online Library Arctic Microbiology and Immunology 43 6 551 559 |
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Wiley Online Library |
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English |
description |
Abstract For the purpose of making clear the dynamics of rabies viruses that are prevalent among dogs in Asia, especially Thailand, nucleoprotein (N) genes of isolates derived from Thailand were partially sequenced, and a phylogenetic analysis was performed on the basis of the sequencing data. Firstly, all 27 isolates from Thailand belonged to one group that was distantly related to an isolate from China and was separated into at least six lineages. On the other hand, the isolate from Japan was related to viruses from the Arctic. Secondly, in order to analyze the diversity of the N gene more conveniently, restriction fragment length polymorphism (RFLP) analysis was performed on the N gene of 27 isolates from Thailand. The RFLP analysis could distinguish the lineages of each isolate, and the lineages of additional 34 isolates were deduced by this method. On examination of the geographical distribution of the six lineages, based on the results of phylogenetic and RFLP analyses, it was clear that infection cycles of the rabies virus in Thailand have tended to be maintained endemically. |
format |
Article in Journal/Newspaper |
author |
Ito, Naoto Sugiyama, Makoto Oraveerakul, Kanisak Piyaviriyakul, Prapruddee Lumlertdacha, Boonlert Arai, Yoko T. Tamura, Yutaka Mori, Yoshio Minamoto, Nobuyuki |
spellingShingle |
Ito, Naoto Sugiyama, Makoto Oraveerakul, Kanisak Piyaviriyakul, Prapruddee Lumlertdacha, Boonlert Arai, Yoko T. Tamura, Yutaka Mori, Yoshio Minamoto, Nobuyuki Molecular Epidemiology of Rabies in Thailand |
author_facet |
Ito, Naoto Sugiyama, Makoto Oraveerakul, Kanisak Piyaviriyakul, Prapruddee Lumlertdacha, Boonlert Arai, Yoko T. Tamura, Yutaka Mori, Yoshio Minamoto, Nobuyuki |
author_sort |
Ito, Naoto |
title |
Molecular Epidemiology of Rabies in Thailand |
title_short |
Molecular Epidemiology of Rabies in Thailand |
title_full |
Molecular Epidemiology of Rabies in Thailand |
title_fullStr |
Molecular Epidemiology of Rabies in Thailand |
title_full_unstemmed |
Molecular Epidemiology of Rabies in Thailand |
title_sort |
molecular epidemiology of rabies in thailand |
publisher |
Wiley |
publishDate |
1999 |
url |
http://dx.doi.org/10.1111/j.1348-0421.1999.tb02441.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1348-0421.1999.tb02441.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1348-0421.1999.tb02441.x |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Microbiology and Immunology volume 43, issue 6, page 551-559 ISSN 0385-5600 1348-0421 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1348-0421.1999.tb02441.x |
container_title |
Microbiology and Immunology |
container_volume |
43 |
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6 |
container_start_page |
551 |
op_container_end_page |
559 |
_version_ |
1809894962913869824 |