Antigen‐induced blastogenesis of salmon, Salmo saluv L., head kidney leucocytes to modified Aeromonas salmonicida antigens: a preliminary evaluation method for potential vaccine antigens

• Published in: Journal of Fish Biology
• Main Author: Tatner, M. F.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1990
• Subjects: Atlantic salmon
• Online Access: http://dx.doi.org/10.1111/j.1095-8649.1990.tb04327.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1095-8649.1990.tb04327.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1095-8649.1990.tb04327.x

Various Aeromonas salmonicida antigen preparations were tested in an antigen‐induced blasto‐genesis assay on the kidney leucocytes of Atlantic salmon. The ECP antigens that had been particularized onto polystyrene beads were the most effective in control fish, and this was further enhanced in fish thymectomized 1 week prior to the assay. The use of this assay for screening potential vaccine antigens is discussed.