Effects of cortisol on immunity in red drum, Sciaenops ocellatus

The immunocompetence of juvenile laboratory‐reared red drum treated with cortisol in the diet (250 and 500 mg kg −1 food) was assessed following intramuscular administration of bacterio‐phage ( Escherichia coli OX 174), washed bovine erythrocytes (1% suspension) and bovine serum albumin (100mg). Cor...

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Bibliographic Details
Published in:Journal of Fish Biology
Main Authors: Thomas, P., Lewis, D. H.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1987
Subjects:
Online Access:http://dx.doi.org/10.1111/j.1095-8649.1987.tb05303.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1095-8649.1987.tb05303.x
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1095-8649.1987.tb05303.x
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Summary:The immunocompetence of juvenile laboratory‐reared red drum treated with cortisol in the diet (250 and 500 mg kg −1 food) was assessed following intramuscular administration of bacterio‐phage ( Escherichia coli OX 174), washed bovine erythrocytes (1% suspension) and bovine serum albumin (100mg). Cortisol induced suppressive effects on the fish response to two of the three antigens (i.e., haemagglutinating activity to bovine erythrocytes and precipitin development to bovine serum albumin). These differential effects of cortisol on T‐dependent antigens could be interpreted as evidence for heterogeneity of red drum T lymphocytes.