The effect of methallibure and cyproterone acetate on the gonadotrophic cells, plasma androgen levels and testes of precocious 1+ male Atlantic salmon parr Salmo salar L.

Developing 1+ male Atlantic salmon parr were treated with methallibure and cyproterone acetate. Both these drugs failed to prevent gonad maturation but they did decrease the gonadotrophic cell size and lower plasma androgen levels. These results are discussed in relation to previous studies. It is c...

Full description

Bibliographic Details
Published in:Journal of Fish Biology
Main Author: Murphy, T. M.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1980
Subjects:
Online Access:http://dx.doi.org/10.1111/j.1095-8649.1980.tb02801.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1095-8649.1980.tb02801.x
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1095-8649.1980.tb02801.x
Description
Summary:Developing 1+ male Atlantic salmon parr were treated with methallibure and cyproterone acetate. Both these drugs failed to prevent gonad maturation but they did decrease the gonadotrophic cell size and lower plasma androgen levels. These results are discussed in relation to previous studies. It is concluded that gonadotrophic cells control gonadal androgen production, that cyproterone acetate is a central inhibitor of gonadotrophin production and that these two chemical agents could be effective as chemosterilants if administered early in gonad maturation cycle.