The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives
Abstract. Coronary risk factors are described in 288 medically treated hypertensives, 1293 untreated hypertensives and 15029 normotensives. Cholesterol in untreated men and women was 0.37 mmol/l and 0.35 mmol/l higher than in normotensives ( p <0.001). Non‐significant differences were observe...
Published in: | Acta Medica Scandinavica |
---|---|
Main Author: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
1988
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1111/j.0954-6820.1988.tb19621.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.0954-6820.1988.tb19621.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.0954-6820.1988.tb19621.x |
id |
crwiley:10.1111/j.0954-6820.1988.tb19621.x |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1111/j.0954-6820.1988.tb19621.x 2023-12-03T10:31:17+01:00 The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives LØCHEN, MAJA‐LISA 1988 http://dx.doi.org/10.1111/j.0954-6820.1988.tb19621.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.0954-6820.1988.tb19621.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.0954-6820.1988.tb19621.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Acta Medica Scandinavica volume 224, issue 6, page 515-521 ISSN 0001-6101 Internal Medicine journal-article 1988 crwiley https://doi.org/10.1111/j.0954-6820.1988.tb19621.x 2023-11-09T13:23:31Z Abstract. Coronary risk factors are described in 288 medically treated hypertensives, 1293 untreated hypertensives and 15029 normotensives. Cholesterol in untreated men and women was 0.37 mmol/l and 0.35 mmol/l higher than in normotensives ( p <0.001). Non‐significant differences were observed between those untreated and treated. Treated men and women had 0.16 mmol/l and 0.14 mmol/l lower HDL cholesterol than untreated ( p <0.01). Between untreated and normotensives non‐significant differences were found. Triglycerides were 0.27 mmol/l and 0.22 mmol/l higher in treated than in untreated men and women ( p <0.01). Normotensive men and women had 0.33 mmol/l and 0.10 mmol/l lower triglycerides than untreated ( p <0.01). The results suggest that the increased cholesterol in hypertensives was present originally, while the decreased HDL cholesterol and elevated triglycerides probably were evoked by drugs. The importance of consideration of the whole constellation of risk factors in order to reduce the mortality from coronary heart disease by antihypertensive drug treatment is emphasized. Article in Journal/Newspaper Tromsø Wiley Online Library (via Crossref) Tromsø Acta Medica Scandinavica 224 6 515 521 |
institution |
Open Polar |
collection |
Wiley Online Library (via Crossref) |
op_collection_id |
crwiley |
language |
English |
topic |
Internal Medicine |
spellingShingle |
Internal Medicine LØCHEN, MAJA‐LISA The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives |
topic_facet |
Internal Medicine |
description |
Abstract. Coronary risk factors are described in 288 medically treated hypertensives, 1293 untreated hypertensives and 15029 normotensives. Cholesterol in untreated men and women was 0.37 mmol/l and 0.35 mmol/l higher than in normotensives ( p <0.001). Non‐significant differences were observed between those untreated and treated. Treated men and women had 0.16 mmol/l and 0.14 mmol/l lower HDL cholesterol than untreated ( p <0.01). Between untreated and normotensives non‐significant differences were found. Triglycerides were 0.27 mmol/l and 0.22 mmol/l higher in treated than in untreated men and women ( p <0.01). Normotensive men and women had 0.33 mmol/l and 0.10 mmol/l lower triglycerides than untreated ( p <0.01). The results suggest that the increased cholesterol in hypertensives was present originally, while the decreased HDL cholesterol and elevated triglycerides probably were evoked by drugs. The importance of consideration of the whole constellation of risk factors in order to reduce the mortality from coronary heart disease by antihypertensive drug treatment is emphasized. |
format |
Article in Journal/Newspaper |
author |
LØCHEN, MAJA‐LISA |
author_facet |
LØCHEN, MAJA‐LISA |
author_sort |
LØCHEN, MAJA‐LISA |
title |
The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives |
title_short |
The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives |
title_full |
The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives |
title_fullStr |
The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives |
title_full_unstemmed |
The Tromsø Heart Study: Coronary Risk Factor Levels in Treated and Untreated Hypertensives |
title_sort |
tromsø heart study: coronary risk factor levels in treated and untreated hypertensives |
publisher |
Wiley |
publishDate |
1988 |
url |
http://dx.doi.org/10.1111/j.0954-6820.1988.tb19621.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.0954-6820.1988.tb19621.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.0954-6820.1988.tb19621.x |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
Acta Medica Scandinavica volume 224, issue 6, page 515-521 ISSN 0001-6101 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.0954-6820.1988.tb19621.x |
container_title |
Acta Medica Scandinavica |
container_volume |
224 |
container_issue |
6 |
container_start_page |
515 |
op_container_end_page |
521 |
_version_ |
1784257513498083328 |