The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study
Abstract Background and aims Previous research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission. Methods Subjects from all age groups (c...
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crwiley:10.1111/hel.12316 2024-06-23T07:55:33+00:00 The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study Breckan, Ragnar K. Paulssen, Eyvind J. Asfeldt, Anne Mette Kvamme, Jan‐Magnus Straume, Bjørn Florholmen, Jon Helse Nord RHF EkstraStiftelsen Helse og Rehabilitering Universitetet i Tromsø 2016 http://dx.doi.org/10.1111/hel.12316 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fhel.12316 https://onlinelibrary.wiley.com/doi/pdf/10.1111/hel.12316 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Helicobacter volume 21, issue 6, page 586-595 ISSN 1083-4389 1523-5378 journal-article 2016 crwiley https://doi.org/10.1111/hel.12316 2024-06-11T04:45:05Z Abstract Background and aims Previous research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission. Methods Subjects from all age groups (children 0–11 years, adolescents 12–17 years and adults ≥18 years of age), recruited from both an urban and a rural community in Northern Norway, were invited to provide stool samples for the diagnosis of H. pylori antigen and to fill in a questionnaire (adult and adolescents only) on gastrointestinal symptoms, lifestyle factors and biometric data. Results A total of 1 624 (35.3%) of the invited subjects, including 173 (39.3%) of the children, 46 (19.2%) of the adolescents, and 1 416 (36.1%) of the adults, responded to the invitation. H. pylori infection was nearly undetectable (0.6%) among the children, whereas the prevalence increased from 20% in adolescents toward a peak of 45% in the highest age group. Univariate analyses of possible risk factors of H. pylori infection showed significant associations to private well water, the use of outhouse toilet, and having farm animals in childhood, but the associations waned in multivariate analyses. Conclusions In our populations, with apparent high hygienic standards, the transmission of H. pylori infection may start not only in childhood, but also in adolescence, where potential transmission routes may be outdoor toilet use, private well water, and farm animals. Article in Journal/Newspaper Northern Norway Wiley Online Library Norway Helicobacter 21 6 586 595 |
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Abstract Background and aims Previous research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission. Methods Subjects from all age groups (children 0–11 years, adolescents 12–17 years and adults ≥18 years of age), recruited from both an urban and a rural community in Northern Norway, were invited to provide stool samples for the diagnosis of H. pylori antigen and to fill in a questionnaire (adult and adolescents only) on gastrointestinal symptoms, lifestyle factors and biometric data. Results A total of 1 624 (35.3%) of the invited subjects, including 173 (39.3%) of the children, 46 (19.2%) of the adolescents, and 1 416 (36.1%) of the adults, responded to the invitation. H. pylori infection was nearly undetectable (0.6%) among the children, whereas the prevalence increased from 20% in adolescents toward a peak of 45% in the highest age group. Univariate analyses of possible risk factors of H. pylori infection showed significant associations to private well water, the use of outhouse toilet, and having farm animals in childhood, but the associations waned in multivariate analyses. Conclusions In our populations, with apparent high hygienic standards, the transmission of H. pylori infection may start not only in childhood, but also in adolescence, where potential transmission routes may be outdoor toilet use, private well water, and farm animals. |
author2 |
Helse Nord RHF EkstraStiftelsen Helse og Rehabilitering Universitetet i Tromsø |
format |
Article in Journal/Newspaper |
author |
Breckan, Ragnar K. Paulssen, Eyvind J. Asfeldt, Anne Mette Kvamme, Jan‐Magnus Straume, Bjørn Florholmen, Jon |
spellingShingle |
Breckan, Ragnar K. Paulssen, Eyvind J. Asfeldt, Anne Mette Kvamme, Jan‐Magnus Straume, Bjørn Florholmen, Jon The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study |
author_facet |
Breckan, Ragnar K. Paulssen, Eyvind J. Asfeldt, Anne Mette Kvamme, Jan‐Magnus Straume, Bjørn Florholmen, Jon |
author_sort |
Breckan, Ragnar K. |
title |
The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study |
title_short |
The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study |
title_full |
The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study |
title_fullStr |
The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study |
title_full_unstemmed |
The All‐Age Prevalence of Helicobacter pylori Infection and Potential Transmission Routes. A Population‐Based Study |
title_sort |
all‐age prevalence of helicobacter pylori infection and potential transmission routes. a population‐based study |
publisher |
Wiley |
publishDate |
2016 |
url |
http://dx.doi.org/10.1111/hel.12316 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fhel.12316 https://onlinelibrary.wiley.com/doi/pdf/10.1111/hel.12316 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Northern Norway |
genre_facet |
Northern Norway |
op_source |
Helicobacter volume 21, issue 6, page 586-595 ISSN 1083-4389 1523-5378 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/hel.12316 |
container_title |
Helicobacter |
container_volume |
21 |
container_issue |
6 |
container_start_page |
586 |
op_container_end_page |
595 |
_version_ |
1802648199736852480 |