Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae

Abstract The consequences of emerging marine diseases on the evolutionary trajectories of affected host populations in the marine realm are largely unexplored. Evolution in response to natural selection depends on the genetic variation of the traits under selection and the interaction of these trait...

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Published in:Evolutionary Applications
Main Authors: Wendling, Carolin C., Fabritzek, Armin G., Wegner, K. Mathias
Other Authors: Deutsche Forschungsgemeinschaft
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 2017
Subjects:
Online Access:http://dx.doi.org/10.1111/eva.12452
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spelling crwiley:10.1111/eva.12452 2024-09-15T18:03:17+00:00 Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae Wendling, Carolin C. Fabritzek, Armin G. Wegner, K. Mathias Deutsche Forschungsgemeinschaft 2017 http://dx.doi.org/10.1111/eva.12452 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Feva.12452 https://onlinelibrary.wiley.com/doi/pdf/10.1111/eva.12452 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Evolutionary Applications volume 10, issue 4, page 338-347 ISSN 1752-4571 1752-4571 journal-article 2017 crwiley https://doi.org/10.1111/eva.12452 2024-09-05T05:09:10Z Abstract The consequences of emerging marine diseases on the evolutionary trajectories of affected host populations in the marine realm are largely unexplored. Evolution in response to natural selection depends on the genetic variation of the traits under selection and the interaction of these traits with the environment (GxE). However, in the case of diseases, pathogen genotypes add another dimension to this interaction. Therefore, the study of disease resistance needs to be extended to the interaction of host genotype, pathogen genotype and environment (GxGxE). In this study, we used a full‐sib breeding design crossing two genetically differentiated populations of the Pacific oyster Crassostrea gigas (Thunberg, 1793), to determine the influence of host genotype, pathogen genotype and temperature on disease resistance. Based on a controlled infection experiment on two early life stages, that is, D‐larvae and Pediveliger larvae at elevated and ambient water temperatures, we estimated disease resistance to allopatric and sympatric Vibrio sp . by measuring survival and growth within and between genetically differentiated oyster populations. In both populations, survival was higher upon infection with sympatric Vibrio sp ., indicating that disease resistance has a genetic basis and is dependent on host genotype. In addition, we observed a significant GxGxE effect in D‐larvae, where contrary to expectations, disease resistance was higher at warm than at cold temperatures. Using thermal reaction norms, we could further show that disease resistance is an environment dependent trait with high plasticity, which indicates the potential for a fast acclimatization to changing environmental conditions. These population‐specific reaction norms disappeared in hybrid crosses between both populations which demonstrates that admixture between genetically differentiated populations can influence GxGxE interactions on larger scales. Article in Journal/Newspaper Crassostrea gigas Pacific oyster Wiley Online Library Evolutionary Applications 10 4 338 347
institution Open Polar
collection Wiley Online Library
op_collection_id crwiley
language English
description Abstract The consequences of emerging marine diseases on the evolutionary trajectories of affected host populations in the marine realm are largely unexplored. Evolution in response to natural selection depends on the genetic variation of the traits under selection and the interaction of these traits with the environment (GxE). However, in the case of diseases, pathogen genotypes add another dimension to this interaction. Therefore, the study of disease resistance needs to be extended to the interaction of host genotype, pathogen genotype and environment (GxGxE). In this study, we used a full‐sib breeding design crossing two genetically differentiated populations of the Pacific oyster Crassostrea gigas (Thunberg, 1793), to determine the influence of host genotype, pathogen genotype and temperature on disease resistance. Based on a controlled infection experiment on two early life stages, that is, D‐larvae and Pediveliger larvae at elevated and ambient water temperatures, we estimated disease resistance to allopatric and sympatric Vibrio sp . by measuring survival and growth within and between genetically differentiated oyster populations. In both populations, survival was higher upon infection with sympatric Vibrio sp ., indicating that disease resistance has a genetic basis and is dependent on host genotype. In addition, we observed a significant GxGxE effect in D‐larvae, where contrary to expectations, disease resistance was higher at warm than at cold temperatures. Using thermal reaction norms, we could further show that disease resistance is an environment dependent trait with high plasticity, which indicates the potential for a fast acclimatization to changing environmental conditions. These population‐specific reaction norms disappeared in hybrid crosses between both populations which demonstrates that admixture between genetically differentiated populations can influence GxGxE interactions on larger scales.
author2 Deutsche Forschungsgemeinschaft
format Article in Journal/Newspaper
author Wendling, Carolin C.
Fabritzek, Armin G.
Wegner, K. Mathias
spellingShingle Wendling, Carolin C.
Fabritzek, Armin G.
Wegner, K. Mathias
Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae
author_facet Wendling, Carolin C.
Fabritzek, Armin G.
Wegner, K. Mathias
author_sort Wendling, Carolin C.
title Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae
title_short Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae
title_full Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae
title_fullStr Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae
title_full_unstemmed Population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of Pacific oyster larvae
title_sort population‐specific genotype x genotype x environment interactions in bacterial disease of early life stages of pacific oyster larvae
publisher Wiley
publishDate 2017
url http://dx.doi.org/10.1111/eva.12452
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Feva.12452
https://onlinelibrary.wiley.com/doi/pdf/10.1111/eva.12452
genre Crassostrea gigas
Pacific oyster
genre_facet Crassostrea gigas
Pacific oyster
op_source Evolutionary Applications
volume 10, issue 4, page 338-347
ISSN 1752-4571 1752-4571
op_rights http://creativecommons.org/licenses/by/4.0/
op_doi https://doi.org/10.1111/eva.12452
container_title Evolutionary Applications
container_volume 10
container_issue 4
container_start_page 338
op_container_end_page 347
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