Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults
Abstract Aims To assess geographic differences in the association between BMI , blood pressure and lipid levels with impaired glucose regulation among young adults from various geographical regions. Methods This was a cross‐sectional study including data from 6987 participants aged ≤ 30 years from I...
Published in: | Diabetic Medicine |
---|---|
Main Authors: | , , , , , , , , |
Other Authors: | , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2015
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1111/dme.12674 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdme.12674 https://onlinelibrary.wiley.com/doi/pdf/10.1111/dme.12674 |
id |
crwiley:10.1111/dme.12674 |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1111/dme.12674 2024-06-02T08:07:28+00:00 Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults Oya, J. Vistisen, D. Christensen, D. L. Faurholt‐Jepsen, D. Mohan, V. Ramachandran, A. Chew, S. K. H. Shaw, J. E. Jørgensen, M. E. National Health and Medical Research Council Senior Research Fellowship Novo Nordisk Foundation 2015 http://dx.doi.org/10.1111/dme.12674 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdme.12674 https://onlinelibrary.wiley.com/doi/pdf/10.1111/dme.12674 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Diabetic Medicine volume 32, issue 4, page 497-504 ISSN 0742-3071 1464-5491 journal-article 2015 crwiley https://doi.org/10.1111/dme.12674 2024-05-03T10:54:11Z Abstract Aims To assess geographic differences in the association between BMI , blood pressure and lipid levels with impaired glucose regulation among young adults from various geographical regions. Methods This was a cross‐sectional study including data from 6987 participants aged ≤ 30 years from India, Singapore, Australia, Greenland, Kenya and Tanzania. Impaired glucose regulation was determined by the 75‐g oral glucose tolerance test. For each geographical region, BMI , blood pressure and lipids were examined and compared between participants with normal glucose tolerance and those with impaired glucose regulation. Multiple logistic regression models were used to assess the association between risk factors and impaired glucose regulation. Results Indian and East African people had a higher prevalence of impaired glucose regulation compared with participants from other regions, despite their lower BMI . Compared with the other regions, blood pressure was lower among Indian and Singaporean people but higher in those from Greenland. Greenlanders had the highest, while Indian and East‐African people, had the lowest level of HDL cholesterol. BMI was positively associated with impaired glucose regulation in all regions, and there were no statistically significant geographic differences. In the Indian, Singaporean and Australian participants, there was a positive association between blood pressure and impaired glucose regulation. Triglycerides were positively associated with and HDL cholesterol had no association with impaired glucose regulation in all geographical regions. Conclusions Higher BMI and triglyceride levels were positively associated with prevalent impaired glucose regulation in all geographical regions. There were geographic differences in the association between impaired glucose regulation and blood pressure and lipids, probably reflecting environmental and genetic factors. Article in Journal/Newspaper Greenland greenlander* Wiley Online Library Greenland Indian Diabetic Medicine 32 4 497 504 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Abstract Aims To assess geographic differences in the association between BMI , blood pressure and lipid levels with impaired glucose regulation among young adults from various geographical regions. Methods This was a cross‐sectional study including data from 6987 participants aged ≤ 30 years from India, Singapore, Australia, Greenland, Kenya and Tanzania. Impaired glucose regulation was determined by the 75‐g oral glucose tolerance test. For each geographical region, BMI , blood pressure and lipids were examined and compared between participants with normal glucose tolerance and those with impaired glucose regulation. Multiple logistic regression models were used to assess the association between risk factors and impaired glucose regulation. Results Indian and East African people had a higher prevalence of impaired glucose regulation compared with participants from other regions, despite their lower BMI . Compared with the other regions, blood pressure was lower among Indian and Singaporean people but higher in those from Greenland. Greenlanders had the highest, while Indian and East‐African people, had the lowest level of HDL cholesterol. BMI was positively associated with impaired glucose regulation in all regions, and there were no statistically significant geographic differences. In the Indian, Singaporean and Australian participants, there was a positive association between blood pressure and impaired glucose regulation. Triglycerides were positively associated with and HDL cholesterol had no association with impaired glucose regulation in all geographical regions. Conclusions Higher BMI and triglyceride levels were positively associated with prevalent impaired glucose regulation in all geographical regions. There were geographic differences in the association between impaired glucose regulation and blood pressure and lipids, probably reflecting environmental and genetic factors. |
author2 |
National Health and Medical Research Council Senior Research Fellowship Novo Nordisk Foundation |
format |
Article in Journal/Newspaper |
author |
Oya, J. Vistisen, D. Christensen, D. L. Faurholt‐Jepsen, D. Mohan, V. Ramachandran, A. Chew, S. K. H. Shaw, J. E. Jørgensen, M. E. |
spellingShingle |
Oya, J. Vistisen, D. Christensen, D. L. Faurholt‐Jepsen, D. Mohan, V. Ramachandran, A. Chew, S. K. H. Shaw, J. E. Jørgensen, M. E. Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
author_facet |
Oya, J. Vistisen, D. Christensen, D. L. Faurholt‐Jepsen, D. Mohan, V. Ramachandran, A. Chew, S. K. H. Shaw, J. E. Jørgensen, M. E. |
author_sort |
Oya, J. |
title |
Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
title_short |
Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
title_full |
Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
title_fullStr |
Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
title_full_unstemmed |
Geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
title_sort |
geographic differences in the associations between impaired glucose regulation and cardiovascular risk factors among young adults |
publisher |
Wiley |
publishDate |
2015 |
url |
http://dx.doi.org/10.1111/dme.12674 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fdme.12674 https://onlinelibrary.wiley.com/doi/pdf/10.1111/dme.12674 |
geographic |
Greenland Indian |
geographic_facet |
Greenland Indian |
genre |
Greenland greenlander* |
genre_facet |
Greenland greenlander* |
op_source |
Diabetic Medicine volume 32, issue 4, page 497-504 ISSN 0742-3071 1464-5491 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/dme.12674 |
container_title |
Diabetic Medicine |
container_volume |
32 |
container_issue |
4 |
container_start_page |
497 |
op_container_end_page |
504 |
_version_ |
1800752550192873472 |