TCF4 trinucleotide repeat expansion in Swedish cases with Fuchs' endothelial corneal dystrophy

• Published in: Acta Ophthalmologica
• Main Authors: Viberg, Andreas, Westin, Ida Maria, Golovleva, Irina, Byström, Berit
• Other Authors: Stiftelsen Kronprinsessan Margaretas Arbetsnämnd för Synskadade, Ögonfonden
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2021
• Subjects: Fuchs; Northern Sweden
• Online Access: http://dx.doi.org/10.1111/aos.15032; https://onlinelibrary.wiley.com/doi/pdf/10.1111/aos.15032; https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aos.15032

Abstract Purpose Fuchs' endothelial corneal dystrophy (FECD) has been considered a genetically heterogeneous disease but is increasingly associated with the transcription factor 4 ( TCF4 ) gene. This study investigates the prevalence of the cytosine‐thymine‐guanine (CTG) n repeat expansion in T...