Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age
Abstract Introduction Endometriosis is a common gynecological condition causing chronic pain and infertility. Only limited data exist on body size during childhood and adolescence in affected women. A leaner body shape has been associated with endometriosis in adults. However, longitudinal follow‐up...
Published in: | Acta Obstetricia et Gynecologica Scandinavica |
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Online Access: | http://dx.doi.org/10.1111/aogs.14090 https://onlinelibrary.wiley.com/doi/pdf/10.1111/aogs.14090 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aogs.14090 https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1111/aogs.14090 |
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crwiley:10.1111/aogs.14090 2024-09-15T18:25:37+00:00 Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age Rossi, Henna‐Riikka Nedelec, Rozenn Jarvelin, Marjo‐Riitta Sebert, Sylvain Uimari, Outi Piltonen, Terhi T. Jalmari ja Rauha Ahokkaan Säätiö Academy of Finland Sigrid Juséliuksen Säätiö 2021 http://dx.doi.org/10.1111/aogs.14090 https://onlinelibrary.wiley.com/doi/pdf/10.1111/aogs.14090 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aogs.14090 https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1111/aogs.14090 en eng Wiley http://creativecommons.org/licenses/by-nc/4.0/ Acta Obstetricia et Gynecologica Scandinavica volume 100, issue 7, page 1248-1257 ISSN 0001-6349 1600-0412 journal-article 2021 crwiley https://doi.org/10.1111/aogs.14090 2024-08-09T04:26:14Z Abstract Introduction Endometriosis is a common gynecological condition causing chronic pain and infertility. Only limited data exist on body size during childhood and adolescence in affected women. A leaner body shape has been associated with endometriosis in adults. However, longitudinal follow‐up data from birth to adulthood are lacking. The aim of this study was to assess the association between body size and endometriosis from birth to age 46 years. We also performed in‐depth analysis of the endometriosis subtypes. Material and Methods This was a population‐based study including 96% of the children born in Northern Finland in 1966. Endometriosis case identification was based on (a) the World Health Organization’s International Statistical Classification of Diseases code documentation from national hospital discharge registers and (b) self‐reported diagnosis. A total of 348 women with endometriosis (203 in subtype analysis) and 3487 women without endometriosis were identified. Pregnancy, birth, and growth data up to adolescence were collected from welfare clinical records. Follow‐up data of the Northern Finland Birth Cohort 1966 were collected at ages 14, 31, and 46 years through postal questionnaires and clinical examinations and included height, weight, and waist and hip circumference measurements. The associations between endometriosis and body size were assessed using logistic regression models. Results Body sizes in childhood and adolescence were comparable between women developing endometriosis and those not developing endometriosis. On average, the risk for endometriosis was 2% lower for every kilogram of weight (odds ratio [OR] 0.98, 95% CI 0.97‐1.00) and 6% lower for every body mass index unit (OR 0.94, 95% CI 0.90‐0.99) at age 31. By age 46, a lower risk for peritoneal endometriosis was observed with greater weight (OR 0.95, 95% CI 0.92‐0.98), weight gain from age 14 to age 46 years (OR 0.97, 95% CI 0.93‐1.00), body mass index (OR 0.90, 95% CI 0.82‐0.98), waist circumference (OR 0.95, 95% CI ... Article in Journal/Newspaper Northern Finland Wiley Online Library Acta Obstetricia et Gynecologica Scandinavica 100 7 1248 1257 |
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Wiley Online Library |
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English |
description |
Abstract Introduction Endometriosis is a common gynecological condition causing chronic pain and infertility. Only limited data exist on body size during childhood and adolescence in affected women. A leaner body shape has been associated with endometriosis in adults. However, longitudinal follow‐up data from birth to adulthood are lacking. The aim of this study was to assess the association between body size and endometriosis from birth to age 46 years. We also performed in‐depth analysis of the endometriosis subtypes. Material and Methods This was a population‐based study including 96% of the children born in Northern Finland in 1966. Endometriosis case identification was based on (a) the World Health Organization’s International Statistical Classification of Diseases code documentation from national hospital discharge registers and (b) self‐reported diagnosis. A total of 348 women with endometriosis (203 in subtype analysis) and 3487 women without endometriosis were identified. Pregnancy, birth, and growth data up to adolescence were collected from welfare clinical records. Follow‐up data of the Northern Finland Birth Cohort 1966 were collected at ages 14, 31, and 46 years through postal questionnaires and clinical examinations and included height, weight, and waist and hip circumference measurements. The associations between endometriosis and body size were assessed using logistic regression models. Results Body sizes in childhood and adolescence were comparable between women developing endometriosis and those not developing endometriosis. On average, the risk for endometriosis was 2% lower for every kilogram of weight (odds ratio [OR] 0.98, 95% CI 0.97‐1.00) and 6% lower for every body mass index unit (OR 0.94, 95% CI 0.90‐0.99) at age 31. By age 46, a lower risk for peritoneal endometriosis was observed with greater weight (OR 0.95, 95% CI 0.92‐0.98), weight gain from age 14 to age 46 years (OR 0.97, 95% CI 0.93‐1.00), body mass index (OR 0.90, 95% CI 0.82‐0.98), waist circumference (OR 0.95, 95% CI ... |
author2 |
Jalmari ja Rauha Ahokkaan Säätiö Academy of Finland Sigrid Juséliuksen Säätiö |
format |
Article in Journal/Newspaper |
author |
Rossi, Henna‐Riikka Nedelec, Rozenn Jarvelin, Marjo‐Riitta Sebert, Sylvain Uimari, Outi Piltonen, Terhi T. |
spellingShingle |
Rossi, Henna‐Riikka Nedelec, Rozenn Jarvelin, Marjo‐Riitta Sebert, Sylvain Uimari, Outi Piltonen, Terhi T. Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
author_facet |
Rossi, Henna‐Riikka Nedelec, Rozenn Jarvelin, Marjo‐Riitta Sebert, Sylvain Uimari, Outi Piltonen, Terhi T. |
author_sort |
Rossi, Henna‐Riikka |
title |
Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
title_short |
Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
title_full |
Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
title_fullStr |
Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
title_full_unstemmed |
Body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
title_sort |
body size during adulthood, but not in childhood, associates with endometriosis, specifically in the peritoneal subtype—population‐based life‐course data from birth to late fertile age |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1111/aogs.14090 https://onlinelibrary.wiley.com/doi/pdf/10.1111/aogs.14090 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aogs.14090 https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1111/aogs.14090 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
Acta Obstetricia et Gynecologica Scandinavica volume 100, issue 7, page 1248-1257 ISSN 0001-6349 1600-0412 |
op_rights |
http://creativecommons.org/licenses/by-nc/4.0/ |
op_doi |
https://doi.org/10.1111/aogs.14090 |
container_title |
Acta Obstetricia et Gynecologica Scandinavica |
container_volume |
100 |
container_issue |
7 |
container_start_page |
1248 |
op_container_end_page |
1257 |
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1810466120525676544 |