A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries
Abstract Background We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID‐19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods R...
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crwiley:10.1111/aas.13983 2024-09-15T18:14:21+00:00 A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries Chew, Michelle S. Kattainen, Salla Haase, Nicolai Buanes, Eirik A. Kristinsdottir, Linda B. Hofsø, Kristin Laake, Jon Henrik Kvåle, Reidar Hästbacka, Johanna Reinikainen, Matti Bendel, Stepani Varpula, Tero Walther, Sten Perner, Anders Flaatten, Hans K. Sigurdsson, Martin I. NordForsk 2021 http://dx.doi.org/10.1111/aas.13983 https://onlinelibrary.wiley.com/doi/pdf/10.1111/aas.13983 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aas.13983 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Acta Anaesthesiologica Scandinavica volume 66, issue 1, page 56-64 ISSN 0001-5172 1399-6576 journal-article 2021 crwiley https://doi.org/10.1111/aas.13983 2024-08-09T04:28:43Z Abstract Background We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID‐19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID‐19 disease during the first wave of COVID‐19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS‐CoV‐2, the ratio of requiring ICU admission for COVID‐19 varied substantially (1.6%–6.7%). Apart from age (proportion of patients aged 65 years or over between 29% and 62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID‐19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59%–85%) in all countries, the proportion of patients receiving renal replacement therapy (7%–26%) and various experimental therapies for COVID‐19 disease varied substantially (e.g. use of hydroxychloroquine 0%–85%). Crude ICU mortality ranged from 11% to 33%. Conclusion There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID‐19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention. Article in Journal/Newspaper Iceland Wiley Online Library Acta Anaesthesiologica Scandinavica 66 1 56 64 |
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Abstract Background We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID‐19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland, Norway and Sweden. Methods Representatives from the national ICU registries for each of the five countries provided clinical data and a description of the strategies to allocate ICU resources and increase the ICU capacity during the pandemic. All adult patients admitted to the ICU for COVID‐19 disease during the first wave of COVID‐19 were included. The clinical characteristics, ICU management and outcomes of individual countries were described with descriptive statistics. Results Most countries more than doubled their ICU capacity during the pandemic. For patients positive for SARS‐CoV‐2, the ratio of requiring ICU admission for COVID‐19 varied substantially (1.6%–6.7%). Apart from age (proportion of patients aged 65 years or over between 29% and 62%), baseline characteristics, chronic comorbidity burden and acute presentations of COVID‐19 disease were similar among the five countries. While utilization of invasive mechanical ventilation was high (59%–85%) in all countries, the proportion of patients receiving renal replacement therapy (7%–26%) and various experimental therapies for COVID‐19 disease varied substantially (e.g. use of hydroxychloroquine 0%–85%). Crude ICU mortality ranged from 11% to 33%. Conclusion There was substantial variability in the critical care response in Nordic ICUs to the first wave of COVID‐19 pandemic, including usage of experimental medications. While ICU mortality was low in all countries, the observed variability warrants further attention. |
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NordForsk |
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Article in Journal/Newspaper |
author |
Chew, Michelle S. Kattainen, Salla Haase, Nicolai Buanes, Eirik A. Kristinsdottir, Linda B. Hofsø, Kristin Laake, Jon Henrik Kvåle, Reidar Hästbacka, Johanna Reinikainen, Matti Bendel, Stepani Varpula, Tero Walther, Sten Perner, Anders Flaatten, Hans K. Sigurdsson, Martin I. |
spellingShingle |
Chew, Michelle S. Kattainen, Salla Haase, Nicolai Buanes, Eirik A. Kristinsdottir, Linda B. Hofsø, Kristin Laake, Jon Henrik Kvåle, Reidar Hästbacka, Johanna Reinikainen, Matti Bendel, Stepani Varpula, Tero Walther, Sten Perner, Anders Flaatten, Hans K. Sigurdsson, Martin I. A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries |
author_facet |
Chew, Michelle S. Kattainen, Salla Haase, Nicolai Buanes, Eirik A. Kristinsdottir, Linda B. Hofsø, Kristin Laake, Jon Henrik Kvåle, Reidar Hästbacka, Johanna Reinikainen, Matti Bendel, Stepani Varpula, Tero Walther, Sten Perner, Anders Flaatten, Hans K. Sigurdsson, Martin I. |
author_sort |
Chew, Michelle S. |
title |
A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries |
title_short |
A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries |
title_full |
A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries |
title_fullStr |
A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries |
title_full_unstemmed |
A descriptive study of the surge response and outcomes of ICU patients with COVID‐19 during first wave in Nordic countries |
title_sort |
descriptive study of the surge response and outcomes of icu patients with covid‐19 during first wave in nordic countries |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1111/aas.13983 https://onlinelibrary.wiley.com/doi/pdf/10.1111/aas.13983 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aas.13983 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Acta Anaesthesiologica Scandinavica volume 66, issue 1, page 56-64 ISSN 0001-5172 1399-6576 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/aas.13983 |
container_title |
Acta Anaesthesiologica Scandinavica |
container_volume |
66 |
container_issue |
1 |
container_start_page |
56 |
op_container_end_page |
64 |
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1810452126472601600 |