A deep‐sea bacterium related to coastal marine pathogens
Summary Evolution of virulence traits from adaptation to environmental niches other than the host is probably a common feature of marine microbial pathogens, whose knowledge might be crucial to understand their emergence and pathogenetic potential. Here, we report genome sequence analysis of a novel...
Published in: | Environmental Microbiology |
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Online Access: | http://dx.doi.org/10.1111/1462-2920.15629 https://onlinelibrary.wiley.com/doi/pdf/10.1111/1462-2920.15629 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/1462-2920.15629 |
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crwiley:10.1111/1462-2920.15629 2024-09-15T18:03:14+00:00 A deep‐sea bacterium related to coastal marine pathogens Lasa, Aide Auguste, Manon Lema, Alberto Oliveri, Caterina Borello, Alessio Taviani, Elisa Bonello, Guido Doni, Lapo Millard, Andrew D. Bruto, Maxime Romalde, Jesus L. Yakimov, Michail Balbi, Teresa Pruzzo, Carla Canesi, Laura Vezzulli, Luigi 2021 http://dx.doi.org/10.1111/1462-2920.15629 https://onlinelibrary.wiley.com/doi/pdf/10.1111/1462-2920.15629 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/1462-2920.15629 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Environmental Microbiology volume 23, issue 9, page 5349-5363 ISSN 1462-2912 1462-2920 journal-article 2021 crwiley https://doi.org/10.1111/1462-2920.15629 2024-08-13T04:19:03Z Summary Evolution of virulence traits from adaptation to environmental niches other than the host is probably a common feature of marine microbial pathogens, whose knowledge might be crucial to understand their emergence and pathogenetic potential. Here, we report genome sequence analysis of a novel marine bacterial species, Vibrio bathopelagicus sp. nov., isolated from warm bathypelagic waters (3309 m depth) of the Mediterranean Sea. Interestingly, V. bathopelagicus sp. nov. is closely related to coastal Vibrio strains pathogenic to marine bivalves. V. bathopelagicus sp. nov. genome encodes genes involved in environmental adaptation to the deep‐sea but also in virulence, such as the R5.7 element, MARTX toxin cluster, Type VI secretion system and zinc‐metalloprotease, previously associated with Vibrio infections in farmed oysters. The results of functional in vitro assays on immunocytes (haemocytes) of the Mediterranean mussel Mytilus galloprovincialis and the Pacific oyster Crassostrea gigas, and of the early larval development assay in Mytilus support strong toxicity of V. bathopelagicus sp. nov. towards bivalves. V. bathopelagicus sp. nov., isolated from a remote Mediterranean bathypelagic site, is an example of a planktonic marine bacterium with genotypic and phenotypic traits associated with animal pathogenicity, which might have played an evolutionary role in the origin of coastal marine pathogens. Article in Journal/Newspaper Crassostrea gigas Pacific oyster Wiley Online Library Environmental Microbiology 23 9 5349 5363 |
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Open Polar |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Summary Evolution of virulence traits from adaptation to environmental niches other than the host is probably a common feature of marine microbial pathogens, whose knowledge might be crucial to understand their emergence and pathogenetic potential. Here, we report genome sequence analysis of a novel marine bacterial species, Vibrio bathopelagicus sp. nov., isolated from warm bathypelagic waters (3309 m depth) of the Mediterranean Sea. Interestingly, V. bathopelagicus sp. nov. is closely related to coastal Vibrio strains pathogenic to marine bivalves. V. bathopelagicus sp. nov. genome encodes genes involved in environmental adaptation to the deep‐sea but also in virulence, such as the R5.7 element, MARTX toxin cluster, Type VI secretion system and zinc‐metalloprotease, previously associated with Vibrio infections in farmed oysters. The results of functional in vitro assays on immunocytes (haemocytes) of the Mediterranean mussel Mytilus galloprovincialis and the Pacific oyster Crassostrea gigas, and of the early larval development assay in Mytilus support strong toxicity of V. bathopelagicus sp. nov. towards bivalves. V. bathopelagicus sp. nov., isolated from a remote Mediterranean bathypelagic site, is an example of a planktonic marine bacterium with genotypic and phenotypic traits associated with animal pathogenicity, which might have played an evolutionary role in the origin of coastal marine pathogens. |
format |
Article in Journal/Newspaper |
author |
Lasa, Aide Auguste, Manon Lema, Alberto Oliveri, Caterina Borello, Alessio Taviani, Elisa Bonello, Guido Doni, Lapo Millard, Andrew D. Bruto, Maxime Romalde, Jesus L. Yakimov, Michail Balbi, Teresa Pruzzo, Carla Canesi, Laura Vezzulli, Luigi |
spellingShingle |
Lasa, Aide Auguste, Manon Lema, Alberto Oliveri, Caterina Borello, Alessio Taviani, Elisa Bonello, Guido Doni, Lapo Millard, Andrew D. Bruto, Maxime Romalde, Jesus L. Yakimov, Michail Balbi, Teresa Pruzzo, Carla Canesi, Laura Vezzulli, Luigi A deep‐sea bacterium related to coastal marine pathogens |
author_facet |
Lasa, Aide Auguste, Manon Lema, Alberto Oliveri, Caterina Borello, Alessio Taviani, Elisa Bonello, Guido Doni, Lapo Millard, Andrew D. Bruto, Maxime Romalde, Jesus L. Yakimov, Michail Balbi, Teresa Pruzzo, Carla Canesi, Laura Vezzulli, Luigi |
author_sort |
Lasa, Aide |
title |
A deep‐sea bacterium related to coastal marine pathogens |
title_short |
A deep‐sea bacterium related to coastal marine pathogens |
title_full |
A deep‐sea bacterium related to coastal marine pathogens |
title_fullStr |
A deep‐sea bacterium related to coastal marine pathogens |
title_full_unstemmed |
A deep‐sea bacterium related to coastal marine pathogens |
title_sort |
deep‐sea bacterium related to coastal marine pathogens |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1111/1462-2920.15629 https://onlinelibrary.wiley.com/doi/pdf/10.1111/1462-2920.15629 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/1462-2920.15629 |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
Environmental Microbiology volume 23, issue 9, page 5349-5363 ISSN 1462-2912 1462-2920 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1111/1462-2920.15629 |
container_title |
Environmental Microbiology |
container_volume |
23 |
container_issue |
9 |
container_start_page |
5349 |
op_container_end_page |
5363 |
_version_ |
1810440753402347520 |