Fasting increases antioxidant enzymes and glutathione content in elephant seals

• Published in: The FASEB Journal
• Main Authors: Vazquez‐Medina, Jose Pablo, Choi, Jinah, Forman, Henry J, Crocker, Daniel E, Ortiz, Rudy M
• Other Authors: National Institutes of Health
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2010
• Subjects: Nes; Nes’; Elephant Seals
• Online Access: http://dx.doi.org/10.1096/fasebj.24.1_supplement.1055.8

Northern elephant seals (NES) are naturally exposed to prolonged fasting (2–3 mo) while weaning, molting or breeding. In terrestrial mammals, fasting increases reactive oxygen species (ROS) production and oxidative damage. Fasting in NES activates the renin‐angiotensin system and increases the expre...