Direct reprogramming of dermal fibroblasts derived from Northern elephant seals into muscle cells

• Published in: The FASEB Journal
• Main Authors: Lam, Emily, Torres‐Velarde, Julia M., Allen, Kaitlin, Arango, B. Gabriela, Crocker, Daniel, Vázquez‐Medina, José P.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2022
• Subjects: Nes; Nes’; Elephant Seal; Elephant Seals
• Online Access: http://dx.doi.org/10.1096/fasebj.2022.36.s1.r6331

Ex vivo tissue culture allows the study of complex cellular mechanisms that are relevant to physiological responses while overcoming the challenges presented by studying animals that are not tractable. In a primary cell culture system, certain proliferating cells can be functionally reprogrammed int...