Fever in pregnancy and offspring mortality – a longitudinal study of a cohort from 1927 to 1937 on the Faroe Islands

• Published in: Acta Obstetricia et Gynecologica Scandinavica
• Main Authors: HELMSDAL, GUNNHILD, OLSEN, SJÚRÐUR F.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2009
• Subjects: Faroe Islands
• Online Access: http://dx.doi.org/10.1080/00016340903160960; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1080%2F00016340903160960; https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1080/00016340903160960

Abstract In a birth cohort from 1927 to 1937 consisting of 4,208 individuals, we examined the relation between complications in pregnancy and offspring adult mortality. Patterns of increased mortality were observed in the group of males whose mothers had experienced fever during pregnancy, i.e. with all‐cause mortality (rate ratio 1.505; 95% CI 1.084–1.926; p = 0.057), premature death (rate ratio 1.943; 95% CI 1.486–2.400; p = 0.004), and with cancer (rate ratio 2.625; 95% CI 1.845–3.405; p = 0.015). To our knowledge, this is the first study to report an association between fever in pregnancy and offspring mortality.