Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons
The hemolysate of the Antarctic teleost Gobionotothen gibberifrons (family Nototheniidae) contains two hemoglobins (Hb 1 and Hb 2). The concentration of Hb 2 (15–20% of the total hemoglobin content) is higher than that found in most cold‐adapted Notothenioidei. Unlike the other Antarctic species so...
Published in: | European Journal of Biochemistry |
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Online Access: | http://dx.doi.org/10.1046/j.1432-1033.2003.03786.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1432-1033.2003.03786.x https://febs.onlinelibrary.wiley.com/doi/pdf/10.1046/j.1432-1033.2003.03786.x |
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crwiley:10.1046/j.1432-1033.2003.03786.x 2024-06-02T07:58:20+00:00 Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons Marinakis, Panagiotis Tamburrini, Maurizio Carratore, Vito di Prisco, Guido 2003 http://dx.doi.org/10.1046/j.1432-1033.2003.03786.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1432-1033.2003.03786.x https://febs.onlinelibrary.wiley.com/doi/pdf/10.1046/j.1432-1033.2003.03786.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor European Journal of Biochemistry volume 270, issue 19, page 3981-3987 ISSN 0014-2956 1432-1033 journal-article 2003 crwiley https://doi.org/10.1046/j.1432-1033.2003.03786.x 2024-05-03T10:53:33Z The hemolysate of the Antarctic teleost Gobionotothen gibberifrons (family Nototheniidae) contains two hemoglobins (Hb 1 and Hb 2). The concentration of Hb 2 (15–20% of the total hemoglobin content) is higher than that found in most cold‐adapted Notothenioidei. Unlike the other Antarctic species so far examined having two hemoglobins, Hb 1 and Hb 2 do not have globin chains in common. Therefore this hemoglobin system is made of four globins (two α‐ and two β‐chains). The complete amino‐acid sequence of the two hemoglobins (Hb 1, Hb 2, ) has been established. The two hemoglobins have different functional properties. Hb 2 has lower oxygen affinity than Hb 1, and higher sensitivity to the modulatory effect of organophosphates. They also differ thermodynamically, as shown by the effects on the oxygen‐binding properties brought about by temperature variations. The oxygen‐transport system of G. gibberifrons , with two functionally distinct hemoglobins, suggests that the two components may have distinct physiological roles, in relation with life style and the environmental conditions which the fish may have to face. The unique features of the oxygen‐transport system of this species are reflected in the phylogeny of the hemoglobin amino‐acid sequences, which are intermediate between those of other fish of the family Nototheniidae and of species of the more advanced family Bathydraconidae. Article in Journal/Newspaper Antarc* Antarctic Wiley Online Library Antarctic The Antarctic European Journal of Biochemistry 270 19 3981 3987 |
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Wiley Online Library |
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crwiley |
language |
English |
description |
The hemolysate of the Antarctic teleost Gobionotothen gibberifrons (family Nototheniidae) contains two hemoglobins (Hb 1 and Hb 2). The concentration of Hb 2 (15–20% of the total hemoglobin content) is higher than that found in most cold‐adapted Notothenioidei. Unlike the other Antarctic species so far examined having two hemoglobins, Hb 1 and Hb 2 do not have globin chains in common. Therefore this hemoglobin system is made of four globins (two α‐ and two β‐chains). The complete amino‐acid sequence of the two hemoglobins (Hb 1, Hb 2, ) has been established. The two hemoglobins have different functional properties. Hb 2 has lower oxygen affinity than Hb 1, and higher sensitivity to the modulatory effect of organophosphates. They also differ thermodynamically, as shown by the effects on the oxygen‐binding properties brought about by temperature variations. The oxygen‐transport system of G. gibberifrons , with two functionally distinct hemoglobins, suggests that the two components may have distinct physiological roles, in relation with life style and the environmental conditions which the fish may have to face. The unique features of the oxygen‐transport system of this species are reflected in the phylogeny of the hemoglobin amino‐acid sequences, which are intermediate between those of other fish of the family Nototheniidae and of species of the more advanced family Bathydraconidae. |
format |
Article in Journal/Newspaper |
author |
Marinakis, Panagiotis Tamburrini, Maurizio Carratore, Vito di Prisco, Guido |
spellingShingle |
Marinakis, Panagiotis Tamburrini, Maurizio Carratore, Vito di Prisco, Guido Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons |
author_facet |
Marinakis, Panagiotis Tamburrini, Maurizio Carratore, Vito di Prisco, Guido |
author_sort |
Marinakis, Panagiotis |
title |
Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons |
title_short |
Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons |
title_full |
Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons |
title_fullStr |
Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons |
title_full_unstemmed |
Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons |
title_sort |
unique features of the hemoglobin system of the antarctic notothenioid fish gobionotothen gibberifrons |
publisher |
Wiley |
publishDate |
2003 |
url |
http://dx.doi.org/10.1046/j.1432-1033.2003.03786.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1432-1033.2003.03786.x https://febs.onlinelibrary.wiley.com/doi/pdf/10.1046/j.1432-1033.2003.03786.x |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_source |
European Journal of Biochemistry volume 270, issue 19, page 3981-3987 ISSN 0014-2956 1432-1033 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1046/j.1432-1033.2003.03786.x |
container_title |
European Journal of Biochemistry |
container_volume |
270 |
container_issue |
19 |
container_start_page |
3981 |
op_container_end_page |
3987 |
_version_ |
1800741651582287872 |