Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L.
Abstract Amoebic gill disease (AGD) affects the marine culture phase of Atlantic salmon, Salmo salar L., in Tasmania. Here, we describe histopathological observations of AGD from smolts, sampled weekly, following transfer to estuarine/marine sites. AGD was initially detected histologically at week 1...
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crwiley:10.1046/j.1365-2761.2003.00496.x 2024-09-09T19:30:32+00:00 Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. Adams, M B Nowak, B F 2003 http://dx.doi.org/10.1046/j.1365-2761.2003.00496.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2003.00496.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2003.00496.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Fish Diseases volume 26, issue 10, page 601-614 ISSN 0140-7775 1365-2761 journal-article 2003 crwiley https://doi.org/10.1046/j.1365-2761.2003.00496.x 2024-08-20T04:17:49Z Abstract Amoebic gill disease (AGD) affects the marine culture phase of Atlantic salmon, Salmo salar L., in Tasmania. Here, we describe histopathological observations of AGD from smolts, sampled weekly, following transfer to estuarine/marine sites. AGD was initially detected histologically at week 13 post‐transfer while gross signs were not observed for a further week post‐transfer. Significant increases ( P < 0.001) in the proportion of affected gill filaments occurred at weeks 18 and 19 post‐transfer coinciding with the cessation of a halocline and increased water temperature at the cage sites. The progression of AGD histopathology, during the sampling period, was characterized by three phases. (1) Primary attachment/interaction associated with extremely localized host cellular alterations, juxtaposed to amoebae, including epithelial desquamation and oedema. (2) Innate immune response activation and initial focal hyperplasia of undifferentiated epithelial cells. (3) Finally, lesion expansion, squamation–stratification of epithelia at lesion surfaces and variable recruitment of mucous cells to these regions. A pattern of preferential colonization of amoebae at lesion margins was apparent during stage 3 of disease development. Together, these data suggest that AGD progression was linked to retraction of the estuarine halocline and increases in water temperature. The host response to gill infection with Neoparamoeba sp. is characterized by a focal fortification strategy concurrent with a migration of immunoregulatory cells to lesion‐affected regions. Article in Journal/Newspaper Atlantic salmon Salmo salar Wiley Online Library Journal of Fish Diseases 26 10 601 614 |
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Wiley Online Library |
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English |
description |
Abstract Amoebic gill disease (AGD) affects the marine culture phase of Atlantic salmon, Salmo salar L., in Tasmania. Here, we describe histopathological observations of AGD from smolts, sampled weekly, following transfer to estuarine/marine sites. AGD was initially detected histologically at week 13 post‐transfer while gross signs were not observed for a further week post‐transfer. Significant increases ( P < 0.001) in the proportion of affected gill filaments occurred at weeks 18 and 19 post‐transfer coinciding with the cessation of a halocline and increased water temperature at the cage sites. The progression of AGD histopathology, during the sampling period, was characterized by three phases. (1) Primary attachment/interaction associated with extremely localized host cellular alterations, juxtaposed to amoebae, including epithelial desquamation and oedema. (2) Innate immune response activation and initial focal hyperplasia of undifferentiated epithelial cells. (3) Finally, lesion expansion, squamation–stratification of epithelia at lesion surfaces and variable recruitment of mucous cells to these regions. A pattern of preferential colonization of amoebae at lesion margins was apparent during stage 3 of disease development. Together, these data suggest that AGD progression was linked to retraction of the estuarine halocline and increases in water temperature. The host response to gill infection with Neoparamoeba sp. is characterized by a focal fortification strategy concurrent with a migration of immunoregulatory cells to lesion‐affected regions. |
format |
Article in Journal/Newspaper |
author |
Adams, M B Nowak, B F |
spellingShingle |
Adams, M B Nowak, B F Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. |
author_facet |
Adams, M B Nowak, B F |
author_sort |
Adams, M B |
title |
Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. |
title_short |
Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. |
title_full |
Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. |
title_fullStr |
Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. |
title_full_unstemmed |
Amoebic gill disease: sequential pathology in cultured Atlantic salmon, Salmo salar L. |
title_sort |
amoebic gill disease: sequential pathology in cultured atlantic salmon, salmo salar l. |
publisher |
Wiley |
publishDate |
2003 |
url |
http://dx.doi.org/10.1046/j.1365-2761.2003.00496.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2003.00496.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2003.00496.x |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Journal of Fish Diseases volume 26, issue 10, page 601-614 ISSN 0140-7775 1365-2761 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1046/j.1365-2761.2003.00496.x |
container_title |
Journal of Fish Diseases |
container_volume |
26 |
container_issue |
10 |
container_start_page |
601 |
op_container_end_page |
614 |
_version_ |
1809899519056281600 |