Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome
The ultrastructural pathology in liver, brain, skeletal and cardiac muscle of Baltic salmon yolk sac fry with the M74 syndrome is described. In the clinical stage of disease, the main pathological findings in the liver were a depletion of glycogen, condensation of nuclear chromatin, hydropic degener...
Published in: | Journal of Fish Diseases |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2002
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1046/j.1365-2761.2002.00264.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2002.00264.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2002.00264.x |
id |
crwiley:10.1046/j.1365-2761.2002.00264.x |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1046/j.1365-2761.2002.00264.x 2024-06-02T08:14:00+00:00 Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome Lundström, J Börjeson, H Norrgren, L 2002 http://dx.doi.org/10.1046/j.1365-2761.2002.00264.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2002.00264.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2002.00264.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Fish Diseases volume 25, issue 3, page 143-154 ISSN 0140-7775 1365-2761 journal-article 2002 crwiley https://doi.org/10.1046/j.1365-2761.2002.00264.x 2024-05-03T11:19:35Z The ultrastructural pathology in liver, brain, skeletal and cardiac muscle of Baltic salmon yolk sac fry with the M74 syndrome is described. In the clinical stage of disease, the main pathological findings in the liver were a depletion of glycogen, condensation of nuclear chromatin, hydropic degeneration of mitochondria and a dilation of the bile canaliculi. In the terminal stage, additional findings were lipid accumulation and myelin whorls in the cytoplasm. The rough endoplasmic reticulum (RER) was degranulated and vesiculated and in some individuals, it formed concentric membranous whorls. Mitochondria showed several additional lesions, such as matrix densities, pleomorphism and cristae abnormalities. Skeletal myocytes were degenerated, and intracellular lipid accumulation was seen in the myocardium. In the brain, an increased frequency of cells exhibiting pyknosis or karryorhexis was recorded. The cytoplasm of these cells formed an amorphous mass of moderate density. The evaluation of brain and skeletal muscle was complicated by sporadic occurrence of pathological findings in the reference material, i.e. clinically healthy Baltic salmon yolk sac fry. As these yolk sac fry are suspected to have a subclinical thiamine deficiency, reference material in future studies should include salmon yolk sac fry from Atlantic populations or originating from reared broodstock. Article in Journal/Newspaper Salmo salar Wiley Online Library Journal of Fish Diseases 25 3 143 154 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
The ultrastructural pathology in liver, brain, skeletal and cardiac muscle of Baltic salmon yolk sac fry with the M74 syndrome is described. In the clinical stage of disease, the main pathological findings in the liver were a depletion of glycogen, condensation of nuclear chromatin, hydropic degeneration of mitochondria and a dilation of the bile canaliculi. In the terminal stage, additional findings were lipid accumulation and myelin whorls in the cytoplasm. The rough endoplasmic reticulum (RER) was degranulated and vesiculated and in some individuals, it formed concentric membranous whorls. Mitochondria showed several additional lesions, such as matrix densities, pleomorphism and cristae abnormalities. Skeletal myocytes were degenerated, and intracellular lipid accumulation was seen in the myocardium. In the brain, an increased frequency of cells exhibiting pyknosis or karryorhexis was recorded. The cytoplasm of these cells formed an amorphous mass of moderate density. The evaluation of brain and skeletal muscle was complicated by sporadic occurrence of pathological findings in the reference material, i.e. clinically healthy Baltic salmon yolk sac fry. As these yolk sac fry are suspected to have a subclinical thiamine deficiency, reference material in future studies should include salmon yolk sac fry from Atlantic populations or originating from reared broodstock. |
format |
Article in Journal/Newspaper |
author |
Lundström, J Börjeson, H Norrgren, L |
spellingShingle |
Lundström, J Börjeson, H Norrgren, L Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome |
author_facet |
Lundström, J Börjeson, H Norrgren, L |
author_sort |
Lundström, J |
title |
Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome |
title_short |
Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome |
title_full |
Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome |
title_fullStr |
Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome |
title_full_unstemmed |
Ultrastructural pathology of Baltic salmon, Salmo salar L., yolk sac fry with the M74 syndrome |
title_sort |
ultrastructural pathology of baltic salmon, salmo salar l., yolk sac fry with the m74 syndrome |
publisher |
Wiley |
publishDate |
2002 |
url |
http://dx.doi.org/10.1046/j.1365-2761.2002.00264.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2002.00264.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2002.00264.x |
genre |
Salmo salar |
genre_facet |
Salmo salar |
op_source |
Journal of Fish Diseases volume 25, issue 3, page 143-154 ISSN 0140-7775 1365-2761 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1046/j.1365-2761.2002.00264.x |
container_title |
Journal of Fish Diseases |
container_volume |
25 |
container_issue |
3 |
container_start_page |
143 |
op_container_end_page |
154 |
_version_ |
1800737682160091136 |