Plasma protein changes in Atlantic salmon, Salmo salar L., with infectious salmon anaemia

• Published in: Journal of Fish Diseases
• Main Authors: Simko, E, Falk, K, Poppe, T T, Ferguson, H W
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2001
• Subjects: Veterinary (miscellaneous); Aquatic Science; Atlantic salmon; Salmo salar
• Online Access: http://dx.doi.org/10.1046/j.1365-2761.2001.00301.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2001.00301.x; https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2001.00301.x

Moderate to severe anaemia and hypoproteinaemia were reported in a Canadian outbreak of ‘haemorrhagic kidney syndrome’ in Atlantic salmon, later shown to be caused by a variant of infectious salmon anaemia virus (ISAV). The progressive anaemia associated with ISA has been previously reported, but hypoproteinaemia in salmon infected with European isolates of ISA virus has not been well documented. The present study showed a very significant positive correlation between decreasing haematocrit values and total plasma protein concentrations in Atlantic salmon infected with two Canadian and two Norwegian ISA viral isolates. However, variations in the concentration of individual plasma proteins, typical of acute phase responses in higher vertebrates, were not observed.