Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.)
Leucocytes derived from head kidney, blood and spleen of turbot, Scophthalmus maximus (L.), exhibited cytotoxic activities against an established cell line (RTG‐2) derived from rainbow trout, Oncorhynchus mykiss (Walbaum). The optimal effector:target ratio, temperature and incubation period for the...
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Online Access: | http://dx.doi.org/10.1046/j.1365-2761.2001.00288.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2001.00288.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2001.00288.x |
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crwiley:10.1046/j.1365-2761.2001.00288.x 2024-06-02T08:14:09+00:00 Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) Tafalla Figueras Novoa 2001 http://dx.doi.org/10.1046/j.1365-2761.2001.00288.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2001.00288.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2001.00288.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Fish Diseases volume 24, issue 3, page 169-175 ISSN 0140-7775 1365-2761 journal-article 2001 crwiley https://doi.org/10.1046/j.1365-2761.2001.00288.x 2024-05-03T11:41:55Z Leucocytes derived from head kidney, blood and spleen of turbot, Scophthalmus maximus (L.), exhibited cytotoxic activities against an established cell line (RTG‐2) derived from rainbow trout, Oncorhynchus mykiss (Walbaum). The optimal effector:target ratio, temperature and incubation period for the activity was determined. Cytotoxicity was not caused by released factors, as effector:target contact was needed. Visualization of the cultures under the transmission electron microscope corroborated the contact between leucocytes and target cells and suggested the implication of monocyte‐like cells in this cell‐mediated cytotoxicity. Article in Journal/Newspaper Scophthalmus maximus Turbot Wiley Online Library Journal of Fish Diseases 24 3 169 175 |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Leucocytes derived from head kidney, blood and spleen of turbot, Scophthalmus maximus (L.), exhibited cytotoxic activities against an established cell line (RTG‐2) derived from rainbow trout, Oncorhynchus mykiss (Walbaum). The optimal effector:target ratio, temperature and incubation period for the activity was determined. Cytotoxicity was not caused by released factors, as effector:target contact was needed. Visualization of the cultures under the transmission electron microscope corroborated the contact between leucocytes and target cells and suggested the implication of monocyte‐like cells in this cell‐mediated cytotoxicity. |
format |
Article in Journal/Newspaper |
author |
Tafalla Figueras Novoa |
spellingShingle |
Tafalla Figueras Novoa Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) |
author_facet |
Tafalla Figueras Novoa |
author_sort |
Tafalla |
title |
Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) |
title_short |
Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) |
title_full |
Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) |
title_fullStr |
Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) |
title_full_unstemmed |
Cytotoxic activity against prelabelled RTG‐2 cells in the turbot, Scophthalmus maximus (L.) |
title_sort |
cytotoxic activity against prelabelled rtg‐2 cells in the turbot, scophthalmus maximus (l.) |
publisher |
Wiley |
publishDate |
2001 |
url |
http://dx.doi.org/10.1046/j.1365-2761.2001.00288.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2761.2001.00288.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2761.2001.00288.x |
genre |
Scophthalmus maximus Turbot |
genre_facet |
Scophthalmus maximus Turbot |
op_source |
Journal of Fish Diseases volume 24, issue 3, page 169-175 ISSN 0140-7775 1365-2761 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1046/j.1365-2761.2001.00288.x |
container_title |
Journal of Fish Diseases |
container_volume |
24 |
container_issue |
3 |
container_start_page |
169 |
op_container_end_page |
175 |
_version_ |
1800737880498241536 |