The role of Helicobacter pylori urease in the pathogenesis of gastritis and peptic ulceration.
Helicobacter pylori produces a 550 kDa, multimeric, nickelācontaining urease that catalyses the hydrolysis of urea to yield ammonia and carbonic acid. The ure gene cluster, comprised of seven genes, encodes the two structural subunits UreA (26.5 kDa) and UreB (60.3 kDa), and five accessory proteins:...
Published in: | Alimentary Pharmacology & Therapeutics |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Wiley
1996
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Online Access: | http://dx.doi.org/10.1046/j.1365-2036.1996.22164006.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2036.1996.22164006.x https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2036.1996.22164006.x |