Cell mediated immunity in Antarctic wintering personnel; 1984–1992
Summary Cell‐mediated immune responses were studied in 12 Antarctic and sub‐Antarctic wintering groups at quarterly intervals over the period 1948–1992, using the cutaneous CMI Multitest. These populations are among the most isolated on earth. While the sub‐Antarctic population at Macquarie Island h...
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Online Access: | http://dx.doi.org/10.1038/icb.1995.48 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Ficb.1995.48 http://www.nature.com/articles/icb199548 http://www.nature.com/articles/icb199548.pdf https://onlinelibrary.wiley.com/doi/pdf/10.1038/icb.1995.48 |
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crwiley:10.1038/icb.1995.48 2024-06-02T07:57:25+00:00 Cell mediated immunity in Antarctic wintering personnel; 1984–1992 MULLER, HK LUGG, DJ QUINN, D 1995 http://dx.doi.org/10.1038/icb.1995.48 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Ficb.1995.48 http://www.nature.com/articles/icb199548 http://www.nature.com/articles/icb199548.pdf https://onlinelibrary.wiley.com/doi/pdf/10.1038/icb.1995.48 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Immunology & Cell Biology volume 73, issue 4, page 316-320 ISSN 0818-9641 1440-1711 journal-article 1995 crwiley https://doi.org/10.1038/icb.1995.48 2024-05-03T11:18:56Z Summary Cell‐mediated immune responses were studied in 12 Antarctic and sub‐Antarctic wintering groups at quarterly intervals over the period 1948–1992, using the cutaneous CMI Multitest. These populations are among the most isolated on earth. While the sub‐Antarctic population at Macquarie Island had levels of responsiveness and hypoergy (9%) comparable to healthy populations in temperate zones, the Antarctic Continental group showed a level of hypoergy of 36%. There was no seasonal variation in the pattern of responses. It is concluded that the extreme and isolated environment and stress factors are responsible for the decreased immunological responsiveness but the mechanisms are presently unclear. On review, one factor appears to be perceived anxiety. The high rate of hypoergy in Antarctica, where medical care is limited, may have health implications. These groups provide an excellent analogue for immunological investigations in longer term space flight. Article in Journal/Newspaper Antarc* Antarctic Antarctica Macquarie Island Wiley Online Library Antarctic The Antarctic Immunology and Cell Biology 73 4 316 320 |
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Open Polar |
collection |
Wiley Online Library |
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crwiley |
language |
English |
description |
Summary Cell‐mediated immune responses were studied in 12 Antarctic and sub‐Antarctic wintering groups at quarterly intervals over the period 1948–1992, using the cutaneous CMI Multitest. These populations are among the most isolated on earth. While the sub‐Antarctic population at Macquarie Island had levels of responsiveness and hypoergy (9%) comparable to healthy populations in temperate zones, the Antarctic Continental group showed a level of hypoergy of 36%. There was no seasonal variation in the pattern of responses. It is concluded that the extreme and isolated environment and stress factors are responsible for the decreased immunological responsiveness but the mechanisms are presently unclear. On review, one factor appears to be perceived anxiety. The high rate of hypoergy in Antarctica, where medical care is limited, may have health implications. These groups provide an excellent analogue for immunological investigations in longer term space flight. |
format |
Article in Journal/Newspaper |
author |
MULLER, HK LUGG, DJ QUINN, D |
spellingShingle |
MULLER, HK LUGG, DJ QUINN, D Cell mediated immunity in Antarctic wintering personnel; 1984–1992 |
author_facet |
MULLER, HK LUGG, DJ QUINN, D |
author_sort |
MULLER, HK |
title |
Cell mediated immunity in Antarctic wintering personnel; 1984–1992 |
title_short |
Cell mediated immunity in Antarctic wintering personnel; 1984–1992 |
title_full |
Cell mediated immunity in Antarctic wintering personnel; 1984–1992 |
title_fullStr |
Cell mediated immunity in Antarctic wintering personnel; 1984–1992 |
title_full_unstemmed |
Cell mediated immunity in Antarctic wintering personnel; 1984–1992 |
title_sort |
cell mediated immunity in antarctic wintering personnel; 1984–1992 |
publisher |
Wiley |
publishDate |
1995 |
url |
http://dx.doi.org/10.1038/icb.1995.48 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Ficb.1995.48 http://www.nature.com/articles/icb199548 http://www.nature.com/articles/icb199548.pdf https://onlinelibrary.wiley.com/doi/pdf/10.1038/icb.1995.48 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic Antarctica Macquarie Island |
genre_facet |
Antarc* Antarctic Antarctica Macquarie Island |
op_source |
Immunology & Cell Biology volume 73, issue 4, page 316-320 ISSN 0818-9641 1440-1711 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1038/icb.1995.48 |
container_title |
Immunology and Cell Biology |
container_volume |
73 |
container_issue |
4 |
container_start_page |
316 |
op_container_end_page |
320 |
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1800740578841853952 |