Origin of Mayans according to HLA genes and the uniqueness of Amerindians
Abstract: The HLA allele frequency distribution of the Mayans from Guatemala was studied and compared with those of other First American Natives and worldwide populations (a total of 12,364 chromosomes and 6182 individuals from 60 different populations). The main conclusions were ( 1 ): the closest...
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crwiley:10.1034/j.1399-0039.2003.00040.x 2024-09-15T18:05:01+00:00 Origin of Mayans according to HLA genes and the uniqueness of Amerindians Gómez‐Casado, E. Martínez‐Laso, J. Moscoso, J. Zamora, J. Martin‐Villa, M. Perez‐Blas, M. Lopez‐Santalla, M. Lucas Gramajo, P. Silvera, C. Lowy, E. Arnaiz‐Villena, A. 2003 http://dx.doi.org/10.1034/j.1399-0039.2003.00040.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1034%2Fj.1399-0039.2003.00040.x https://onlinelibrary.wiley.com/doi/pdf/10.1034/j.1399-0039.2003.00040.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Tissue Antigens volume 61, issue 6, page 425-436 ISSN 0001-2815 1399-0039 journal-article 2003 crwiley https://doi.org/10.1034/j.1399-0039.2003.00040.x 2024-06-27T04:21:24Z Abstract: The HLA allele frequency distribution of the Mayans from Guatemala was studied and compared with those of other First American Natives and worldwide populations (a total of 12,364 chromosomes and 6182 individuals from 60 different populations). The main conclusions were ( 1 ): the closest Amerindian group to Mayans is the Arhuacs, who were the first recorded Caribbean Islands' inhabitants ( 2 ). Mayans are not so close to Mesoamerican Zapotec, Mixe and Mixtec Amerindians, who genetically cluster together. Mixe had been related to Mayans only on linguistic bases ( 3 ). DRB1*0407 and DRB1*0802 alleles are found in 50% of Mayans; these alleles are also found in other Amerindians, but the Mayans' high frequencies may be showing a founder effect for this Mesoamerican‐Caribbean population ( 4 ). Extended Mayan specific HLA haplotypes are described for the first time ( 5 ). Language and genes do not completely correlate in microgeographical studies ( 6 ). Significant genetic input from outside is not noticed in Meso and South American Amerindians according to the genetic analyses; while all world populations (including Africans, Europeans, Asians, Australians, Polynesians, North American Na‐Dene Indians and Eskimos) are genetically related. Meso and South American Amerindians tend to remain isolated in the neighbour joining analyses. Article in Journal/Newspaper eskimo* Wiley Online Library Tissue Antigens 61 6 425 436 |
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English |
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Abstract: The HLA allele frequency distribution of the Mayans from Guatemala was studied and compared with those of other First American Natives and worldwide populations (a total of 12,364 chromosomes and 6182 individuals from 60 different populations). The main conclusions were ( 1 ): the closest Amerindian group to Mayans is the Arhuacs, who were the first recorded Caribbean Islands' inhabitants ( 2 ). Mayans are not so close to Mesoamerican Zapotec, Mixe and Mixtec Amerindians, who genetically cluster together. Mixe had been related to Mayans only on linguistic bases ( 3 ). DRB1*0407 and DRB1*0802 alleles are found in 50% of Mayans; these alleles are also found in other Amerindians, but the Mayans' high frequencies may be showing a founder effect for this Mesoamerican‐Caribbean population ( 4 ). Extended Mayan specific HLA haplotypes are described for the first time ( 5 ). Language and genes do not completely correlate in microgeographical studies ( 6 ). Significant genetic input from outside is not noticed in Meso and South American Amerindians according to the genetic analyses; while all world populations (including Africans, Europeans, Asians, Australians, Polynesians, North American Na‐Dene Indians and Eskimos) are genetically related. Meso and South American Amerindians tend to remain isolated in the neighbour joining analyses. |
format |
Article in Journal/Newspaper |
author |
Gómez‐Casado, E. Martínez‐Laso, J. Moscoso, J. Zamora, J. Martin‐Villa, M. Perez‐Blas, M. Lopez‐Santalla, M. Lucas Gramajo, P. Silvera, C. Lowy, E. Arnaiz‐Villena, A. |
spellingShingle |
Gómez‐Casado, E. Martínez‐Laso, J. Moscoso, J. Zamora, J. Martin‐Villa, M. Perez‐Blas, M. Lopez‐Santalla, M. Lucas Gramajo, P. Silvera, C. Lowy, E. Arnaiz‐Villena, A. Origin of Mayans according to HLA genes and the uniqueness of Amerindians |
author_facet |
Gómez‐Casado, E. Martínez‐Laso, J. Moscoso, J. Zamora, J. Martin‐Villa, M. Perez‐Blas, M. Lopez‐Santalla, M. Lucas Gramajo, P. Silvera, C. Lowy, E. Arnaiz‐Villena, A. |
author_sort |
Gómez‐Casado, E. |
title |
Origin of Mayans according to HLA genes and the uniqueness of Amerindians |
title_short |
Origin of Mayans according to HLA genes and the uniqueness of Amerindians |
title_full |
Origin of Mayans according to HLA genes and the uniqueness of Amerindians |
title_fullStr |
Origin of Mayans according to HLA genes and the uniqueness of Amerindians |
title_full_unstemmed |
Origin of Mayans according to HLA genes and the uniqueness of Amerindians |
title_sort |
origin of mayans according to hla genes and the uniqueness of amerindians |
publisher |
Wiley |
publishDate |
2003 |
url |
http://dx.doi.org/10.1034/j.1399-0039.2003.00040.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1034%2Fj.1399-0039.2003.00040.x https://onlinelibrary.wiley.com/doi/pdf/10.1034/j.1399-0039.2003.00040.x |
genre |
eskimo* |
genre_facet |
eskimo* |
op_source |
Tissue Antigens volume 61, issue 6, page 425-436 ISSN 0001-2815 1399-0039 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1034/j.1399-0039.2003.00040.x |
container_title |
Tissue Antigens |
container_volume |
61 |
container_issue |
6 |
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425 |
op_container_end_page |
436 |
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1810442606385037312 |