Continuous production of acyl l‐ascorbates using a packed‐bed reactor with immobilized lipase

• Published in: Journal of the American Oil Chemists' Society
• Main Authors: Kuwabara, Ko, Watanabe, Yoshiyuki, Adachi, Shuji, Nakanishi, Kazuhiro, Matsuno, Ryuichi
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2003
• Subjects: Antarc*; Antarctica
• Online Access: http://dx.doi.org/10.1007/s11746-003-0791-0; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1007%2Fs11746-003-0791-0; https://onlinelibrary.wiley.com/doi/full/10.1007/s11746-003-0791-0

Abstract Saturated acyl (6‐ O ‐caproyl, lauroyl, and myristoyl) and unsaturated acyl (6‐ O ‐oleoyl, linoleoyl, and arachidonoyl) l‐ascorbates were continuously synthesized at 50°C using a system where a column packed with ascorbic acid powder and a packed‐bed reactor with an immobilized lipase from Candida antarctica were connected in series. A productivity of 1.6–1.9 kg/L reactor·d was achieved for at least 11 d. The surface tension of the caproyl or lauroyl l‐ascorbate in aqueous solution was measured at various temperatures and pH to estimate the critical micelle concentration (CMC) of the acyl l‐ascorbate. The CMC values were independent of temperature but dependent on the pH. The value of the caproyl ascorbate increased with an increase in pH.