Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs
Abstract Background The Omega‐3 Index is a test that measures the amount of the long‐chain omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, which is expressed as a percentage of all fatty acids. However, alpha‐li...
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crwiley:10.1002/vms3.369 2024-06-23T07:46:15+00:00 Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs Dominguez, Tonje E. Kaur, Kiranpreet Burri, Lena 2020 http://dx.doi.org/10.1002/vms3.369 https://onlinelibrary.wiley.com/doi/pdf/10.1002/vms3.369 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/vms3.369 en eng Wiley http://creativecommons.org/licenses/by-nc-nd/4.0/ Veterinary Medicine and Science volume 7, issue 2, page 370-377 ISSN 2053-1095 2053-1095 journal-article 2020 crwiley https://doi.org/10.1002/vms3.369 2024-06-11T04:43:30Z Abstract Background The Omega‐3 Index is a test that measures the amount of the long‐chain omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, which is expressed as a percentage of all fatty acids. However, alpha‐linolenic acid (ALA) from flaxseed oil, which is a short‐chain n‐3 PUFA, is often promoted in pet feed as a n‐3 source, implicitly assuming it is an effective precursor of EPA and DHA. Objective This study was aimed to compare the effect of supplementation with a plant‐based short‐chain n‐3 PUFA source (flaxseed oil, FSO) with a marine long‐chain n‐3 PUFA source (astaxanthin krill oil, AKO) to increase the Omega‐3 Index in dogs. Methods Ten adult Alaskan Huskies of both genders were supplemented daily with 1,155 mg of EPA/DHA from AKO, whereas another 10 dogs received 1,068 mg ALA from flaxseed oil for 6 weeks. Fatty acid and Omega‐3 Index measurements of the two groups were taken after 0, 3 and 6 weeks for comparison. Results The EPA and DHA concentrations increased significantly only in the dogs fed with AKO resulting in a significant increase in mean Omega‐3 Index, from 1.68% at baseline to 2.7% after 6 weeks of supplementation ( p < .0001). On the contrary, both EPA and DHA concentrations decreased significantly in the dogs fed with FSO, which led to a significant decrease in mean Omega‐3 Index from 1.6% at baseline to 0.96% at study end ( p < .0001). Conclusions The results showed that supplementation of AKO from Antarctic krill led to a significant increase in the Omega‐3 Index in comparison to FSO in dogs. This suggests that preformed marine EPA and DHA sources are needed in dog feeds, as the dietary requirements proposed by feed industry organizations are not met with conversion from short‐chain n‐3 fatty acids. Article in Journal/Newspaper Antarc* Antarctic Antarctic Krill Huskies Wiley Online Library Antarctic Veterinary Medicine and Science 7 2 370 377 |
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Wiley Online Library |
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crwiley |
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English |
description |
Abstract Background The Omega‐3 Index is a test that measures the amount of the long‐chain omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, which is expressed as a percentage of all fatty acids. However, alpha‐linolenic acid (ALA) from flaxseed oil, which is a short‐chain n‐3 PUFA, is often promoted in pet feed as a n‐3 source, implicitly assuming it is an effective precursor of EPA and DHA. Objective This study was aimed to compare the effect of supplementation with a plant‐based short‐chain n‐3 PUFA source (flaxseed oil, FSO) with a marine long‐chain n‐3 PUFA source (astaxanthin krill oil, AKO) to increase the Omega‐3 Index in dogs. Methods Ten adult Alaskan Huskies of both genders were supplemented daily with 1,155 mg of EPA/DHA from AKO, whereas another 10 dogs received 1,068 mg ALA from flaxseed oil for 6 weeks. Fatty acid and Omega‐3 Index measurements of the two groups were taken after 0, 3 and 6 weeks for comparison. Results The EPA and DHA concentrations increased significantly only in the dogs fed with AKO resulting in a significant increase in mean Omega‐3 Index, from 1.68% at baseline to 2.7% after 6 weeks of supplementation ( p < .0001). On the contrary, both EPA and DHA concentrations decreased significantly in the dogs fed with FSO, which led to a significant decrease in mean Omega‐3 Index from 1.6% at baseline to 0.96% at study end ( p < .0001). Conclusions The results showed that supplementation of AKO from Antarctic krill led to a significant increase in the Omega‐3 Index in comparison to FSO in dogs. This suggests that preformed marine EPA and DHA sources are needed in dog feeds, as the dietary requirements proposed by feed industry organizations are not met with conversion from short‐chain n‐3 fatty acids. |
format |
Article in Journal/Newspaper |
author |
Dominguez, Tonje E. Kaur, Kiranpreet Burri, Lena |
spellingShingle |
Dominguez, Tonje E. Kaur, Kiranpreet Burri, Lena Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
author_facet |
Dominguez, Tonje E. Kaur, Kiranpreet Burri, Lena |
author_sort |
Dominguez, Tonje E. |
title |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_short |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_full |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_fullStr |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_full_unstemmed |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_sort |
enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
publisher |
Wiley |
publishDate |
2020 |
url |
http://dx.doi.org/10.1002/vms3.369 https://onlinelibrary.wiley.com/doi/pdf/10.1002/vms3.369 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/vms3.369 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Antarctic Krill Huskies |
genre_facet |
Antarc* Antarctic Antarctic Krill Huskies |
op_source |
Veterinary Medicine and Science volume 7, issue 2, page 370-377 ISSN 2053-1095 2053-1095 |
op_rights |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_doi |
https://doi.org/10.1002/vms3.369 |
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Veterinary Medicine and Science |
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7 |
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2 |
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370 |
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377 |
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1802644852089815040 |