Enantioselective Enzymatic Synthesis of ( R)‐Phenyl Alkyl Esters and Their Analogue Amides using Fatty Acids as Green Acyl Donors.

• Published in: ChemistrySelect
• Main Authors: Benamara, Nour ElHouda, Merabet‐Khelassi, Mounia, Lakoud, Samia Guezane, Aribi‐Zouioueche, Louisa, Riant, Olivier
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2021
• Subjects: Rugosa; Antarc*; Antarctica
• Online Access: http://dx.doi.org/10.1002/slct.202103831; https://onlinelibrary.wiley.com/doi/pdf/10.1002/slct.202103831; https://onlinelibrary.wiley.com/doi/full-xml/10.1002/slct.202103831

Abstract An efficient enantioselective synthesis of a set of ( R ) ‐ phenylalkylesters and their analogues amides via enzymatic acylation of 1‐phenylethanol ( rac‐ 1 ) and 1‐phenylethanamine ( rac‐ 2 ) using carboxylic acids with different chain‐lengths as green acyl donor is reported. Three lipases...