Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data
Abstract For performing regression analysis of summarized response data containing grouped intervals of exposure, many researchers use pre‐assigned doses such as the median values of each interval. However, the trend estimate is considerably sensitive to the choice of the assigned values. In this pa...
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crwiley:10.1002/sim.4000 2024-06-02T08:07:30+00:00 Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data Takahashi, Kunihiko Tango, Toshiro 2010 http://dx.doi.org/10.1002/sim.4000 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fsim.4000 https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.4000 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor http://doi.wiley.com/10.1002/tdm_license_1.1 http://onlinelibrary.wiley.com/termsAndConditions#vor Statistics in Medicine volume 29, issue 25, page 2605-2616 ISSN 0277-6715 1097-0258 journal-article 2010 crwiley https://doi.org/10.1002/sim.4000 2024-05-03T11:57:12Z Abstract For performing regression analysis of summarized response data containing grouped intervals of exposure, many researchers use pre‐assigned doses such as the median values of each interval. However, the trend estimate is considerably sensitive to the choice of the assigned values. In this paper, we propose a method to assign the values to obtain a more accurate regression coefficient applying the likelihood approach. Numerical illustrations and comparisons through simulations showed that the proposed dose assignment can yield better estimates of trend in the regression analysis of two variants than that obtained by the conventional assignment methods such as those that use median values. In particular, for the data of a case–control study, the proposed dose improved the accuracy of the procedures such as that developed by Greenland and Longnecker (1992) compared with the conventional pre‐assigned dose. Copyright © 2010 John Wiley & Sons, Ltd. Article in Journal/Newspaper Greenland Wiley Online Library Greenland Statistics in Medicine 29 25 2605 2616 |
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English |
description |
Abstract For performing regression analysis of summarized response data containing grouped intervals of exposure, many researchers use pre‐assigned doses such as the median values of each interval. However, the trend estimate is considerably sensitive to the choice of the assigned values. In this paper, we propose a method to assign the values to obtain a more accurate regression coefficient applying the likelihood approach. Numerical illustrations and comparisons through simulations showed that the proposed dose assignment can yield better estimates of trend in the regression analysis of two variants than that obtained by the conventional assignment methods such as those that use median values. In particular, for the data of a case–control study, the proposed dose improved the accuracy of the procedures such as that developed by Greenland and Longnecker (1992) compared with the conventional pre‐assigned dose. Copyright © 2010 John Wiley & Sons, Ltd. |
format |
Article in Journal/Newspaper |
author |
Takahashi, Kunihiko Tango, Toshiro |
spellingShingle |
Takahashi, Kunihiko Tango, Toshiro Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
author_facet |
Takahashi, Kunihiko Tango, Toshiro |
author_sort |
Takahashi, Kunihiko |
title |
Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
title_short |
Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
title_full |
Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
title_fullStr |
Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
title_full_unstemmed |
Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
title_sort |
assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data |
publisher |
Wiley |
publishDate |
2010 |
url |
http://dx.doi.org/10.1002/sim.4000 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fsim.4000 https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.4000 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland |
genre_facet |
Greenland |
op_source |
Statistics in Medicine volume 29, issue 25, page 2605-2616 ISSN 0277-6715 1097-0258 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor http://doi.wiley.com/10.1002/tdm_license_1.1 http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/sim.4000 |
container_title |
Statistics in Medicine |
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29 |
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25 |
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2605 |
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2616 |
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1800752596462338048 |