Antibacterial potential of Antarctic lichens against human pathogenic Gram‐positive bacteria
Abstract Extracts from five Antarctic lichens (L3, Stereocaulon alpinum L5, Ramalina terebrata L6, Caloplaca sp.; L8, Lecanora sp.; and L17, Caloplaca regalis ) were tested for antimicrobial activities against several clinically important microbes by disk diffusion. The minimum inhibitory concentrat...
Published in: | Phytotherapy Research |
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Main Authors: | , , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2008
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Subjects: | |
Online Access: | http://dx.doi.org/10.1002/ptr.2445 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fptr.2445 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.2445 |
Summary: | Abstract Extracts from five Antarctic lichens (L3, Stereocaulon alpinum L5, Ramalina terebrata L6, Caloplaca sp.; L8, Lecanora sp.; and L17, Caloplaca regalis ) were tested for antimicrobial activities against several clinically important microbes by disk diffusion. The minimum inhibitory concentration (MIC) of each extract was determined by a broth dilution method. Extracts from L3, L5, L6 and L8 were active against two Gram(+) strains. B. subtilis was more sensitive to lichen extracts (except L5) than S. aureus . The MIC of lichen extracts against B. subtilis and S. aureus was observed from 36.7 ± 0.3 to 953.8 ± 85.8 µg/mL and 68.5 ± 0.6 to >1000 µg/mL, respectively. Comparisons of MIC values of Antarctic lichen crude extracts to previously published MIC values of some reported lichen metabolites against Gram(+) bacteria indicated that Antarctic lichens might be an enriched source of effective antibacterial agents against clinically relevant Gram(+) species. Copyright © 2008 John Wiley & Sons, Ltd. |
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