Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications
Abstract A series of biomedical polyurethane elastomers (PURs) based on poly(ester‐carbonate)s (PECs) and polycarbonates (PCs) were synthesized and spectrally characterized fully. PEC or PC diols were synthesized by the ring‐opening polymerization of ε‐caprolactone, trimethylene carbonate, and neope...
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crwiley:10.1002/pola.26190 2024-06-23T07:47:58+00:00 Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications Sobczak, Marcin Dębek, Cezary Olędzka, Ewa Nałęcz‐Jawecki, Grzegorz Kołodziejski, Wacław L. Rajkiewicz, Maria 2012 http://dx.doi.org/10.1002/pola.26190 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fpola.26190 https://onlinelibrary.wiley.com/doi/pdf/10.1002/pola.26190 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Polymer Science Part A: Polymer Chemistry volume 50, issue 18, page 3904-3913 ISSN 0887-624X 1099-0518 journal-article 2012 crwiley https://doi.org/10.1002/pola.26190 2024-06-11T04:51:04Z Abstract A series of biomedical polyurethane elastomers (PURs) based on poly(ester‐carbonate)s (PECs) and polycarbonates (PCs) were synthesized and spectrally characterized fully. PEC or PC diols were synthesized by the ring‐opening polymerization of ε‐caprolactone, trimethylene carbonate, and neopentyl carbonate catalyzed by lipase from Candida antarctica . PURs were prepared by free‐metal method from PEC or PC diols and 4,4′‐methylenebis(phenyl isocyanate), with 1,4‐butanediol as a chain extender. The physical and mechanical properties as well as hydrolytic stability of the obtained PURs were determined. The toxicity of the received polymers was evaluated using bacterial luminescence test and two protozoans assays. The presented preliminary studies suggest that PEC or PC diols prepared in this way might be applied for the synthesis of biomedical PURs with improved hydrolytic stability. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012 Article in Journal/Newspaper Antarc* Antarctica Wiley Online Library Journal of Polymer Science Part A: Polymer Chemistry 50 18 3904 3913 |
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English |
description |
Abstract A series of biomedical polyurethane elastomers (PURs) based on poly(ester‐carbonate)s (PECs) and polycarbonates (PCs) were synthesized and spectrally characterized fully. PEC or PC diols were synthesized by the ring‐opening polymerization of ε‐caprolactone, trimethylene carbonate, and neopentyl carbonate catalyzed by lipase from Candida antarctica . PURs were prepared by free‐metal method from PEC or PC diols and 4,4′‐methylenebis(phenyl isocyanate), with 1,4‐butanediol as a chain extender. The physical and mechanical properties as well as hydrolytic stability of the obtained PURs were determined. The toxicity of the received polymers was evaluated using bacterial luminescence test and two protozoans assays. The presented preliminary studies suggest that PEC or PC diols prepared in this way might be applied for the synthesis of biomedical PURs with improved hydrolytic stability. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012 |
format |
Article in Journal/Newspaper |
author |
Sobczak, Marcin Dębek, Cezary Olędzka, Ewa Nałęcz‐Jawecki, Grzegorz Kołodziejski, Wacław L. Rajkiewicz, Maria |
spellingShingle |
Sobczak, Marcin Dębek, Cezary Olędzka, Ewa Nałęcz‐Jawecki, Grzegorz Kołodziejski, Wacław L. Rajkiewicz, Maria Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
author_facet |
Sobczak, Marcin Dębek, Cezary Olędzka, Ewa Nałęcz‐Jawecki, Grzegorz Kołodziejski, Wacław L. Rajkiewicz, Maria |
author_sort |
Sobczak, Marcin |
title |
Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
title_short |
Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
title_full |
Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
title_fullStr |
Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
title_full_unstemmed |
Segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
title_sort |
segmented polyurethane elastomers derived from aliphatic polycarbonate and poly(ester‐carbonate) soft segments for biomedical applications |
publisher |
Wiley |
publishDate |
2012 |
url |
http://dx.doi.org/10.1002/pola.26190 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fpola.26190 https://onlinelibrary.wiley.com/doi/pdf/10.1002/pola.26190 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Journal of Polymer Science Part A: Polymer Chemistry volume 50, issue 18, page 3904-3913 ISSN 0887-624X 1099-0518 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/pola.26190 |
container_title |
Journal of Polymer Science Part A: Polymer Chemistry |
container_volume |
50 |
container_issue |
18 |
container_start_page |
3904 |
op_container_end_page |
3913 |
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1802638302325506048 |