Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria
ABSTRACT Introduction : In young patients with mononeuropathy who lack family history and precipitating factors, hereditary neuropathy with liability to pressure palsy (HNPP) may be a possibility. Our objective is to propose neurophysiological criteria for HNPP in patients <30 years of age. Metho...
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crwiley:10.1002/mus.25666 2024-09-15T18:03:47+00:00 Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria Robert‐Varvat, Florence Jousserand, Guillemette Bouhour, Françoise Vial, Christophe Cintas, Pascal Echaniz‐Laguna, Andoni Delmont, Emilien Clavelou, Pierre Chauplannaz, Guy Jomir, Laurent Pereon, Yann Leonard‐Louis, Sarah Manel, Veronique Antoine, Jean‐Christophe Lacour, Arnaud Camdessanche, Jean‐Philippe 2017 http://dx.doi.org/10.1002/mus.25666 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmus.25666 https://onlinelibrary.wiley.com/doi/pdf/10.1002/mus.25666 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Muscle & Nerve volume 57, issue 2, page 217-221 ISSN 0148-639X 1097-4598 journal-article 2017 crwiley https://doi.org/10.1002/mus.25666 2024-07-30T04:23:17Z ABSTRACT Introduction : In young patients with mononeuropathy who lack family history and precipitating factors, hereditary neuropathy with liability to pressure palsy (HNPP) may be a possibility. Our objective is to propose neurophysiological criteria for HNPP in patients <30 years of age. Methods : We conducted a national multicenter retrospective clinical and neurophysiological study in patients under 30 with genetically confirmed HNPP. Results : All of the 51 patients included in the study had at least 1 demyelinating pattern in 2 asymptomatic nerves, and 3 abnormalities were found in almost 90%, including slowed motor nerve conduction velocity across the elbow in at least 1 ulnar nerve (97.5%), increased distal motor latency (DML) in at least 1 fibular nerve (95.8%), and increased DML in both median nerves (89%). Age influenced DML slightly only in the fibular nerve. Discussion : Dissemination of nerve involvement in HNPP incites to perform a complete nerve conduction study. including bilateral ulnar, fibular, and median nerves. Muscle Nerve 57 : 217–221, 2018 Article in Journal/Newspaper DML Wiley Online Library Muscle & Nerve 57 2 217 221 |
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Wiley Online Library |
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description |
ABSTRACT Introduction : In young patients with mononeuropathy who lack family history and precipitating factors, hereditary neuropathy with liability to pressure palsy (HNPP) may be a possibility. Our objective is to propose neurophysiological criteria for HNPP in patients <30 years of age. Methods : We conducted a national multicenter retrospective clinical and neurophysiological study in patients under 30 with genetically confirmed HNPP. Results : All of the 51 patients included in the study had at least 1 demyelinating pattern in 2 asymptomatic nerves, and 3 abnormalities were found in almost 90%, including slowed motor nerve conduction velocity across the elbow in at least 1 ulnar nerve (97.5%), increased distal motor latency (DML) in at least 1 fibular nerve (95.8%), and increased DML in both median nerves (89%). Age influenced DML slightly only in the fibular nerve. Discussion : Dissemination of nerve involvement in HNPP incites to perform a complete nerve conduction study. including bilateral ulnar, fibular, and median nerves. Muscle Nerve 57 : 217–221, 2018 |
format |
Article in Journal/Newspaper |
author |
Robert‐Varvat, Florence Jousserand, Guillemette Bouhour, Françoise Vial, Christophe Cintas, Pascal Echaniz‐Laguna, Andoni Delmont, Emilien Clavelou, Pierre Chauplannaz, Guy Jomir, Laurent Pereon, Yann Leonard‐Louis, Sarah Manel, Veronique Antoine, Jean‐Christophe Lacour, Arnaud Camdessanche, Jean‐Philippe |
spellingShingle |
Robert‐Varvat, Florence Jousserand, Guillemette Bouhour, Françoise Vial, Christophe Cintas, Pascal Echaniz‐Laguna, Andoni Delmont, Emilien Clavelou, Pierre Chauplannaz, Guy Jomir, Laurent Pereon, Yann Leonard‐Louis, Sarah Manel, Veronique Antoine, Jean‐Christophe Lacour, Arnaud Camdessanche, Jean‐Philippe Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria |
author_facet |
Robert‐Varvat, Florence Jousserand, Guillemette Bouhour, Françoise Vial, Christophe Cintas, Pascal Echaniz‐Laguna, Andoni Delmont, Emilien Clavelou, Pierre Chauplannaz, Guy Jomir, Laurent Pereon, Yann Leonard‐Louis, Sarah Manel, Veronique Antoine, Jean‐Christophe Lacour, Arnaud Camdessanche, Jean‐Philippe |
author_sort |
Robert‐Varvat, Florence |
title |
Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria |
title_short |
Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria |
title_full |
Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria |
title_fullStr |
Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria |
title_full_unstemmed |
Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria |
title_sort |
hereditary neuropathy with liability to pressure palsy in patients under 30 years old: neurophysiological data and proposed electrodiagnostic criteria |
publisher |
Wiley |
publishDate |
2017 |
url |
http://dx.doi.org/10.1002/mus.25666 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmus.25666 https://onlinelibrary.wiley.com/doi/pdf/10.1002/mus.25666 |
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DML |
genre_facet |
DML |
op_source |
Muscle & Nerve volume 57, issue 2, page 217-221 ISSN 0148-639X 1097-4598 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/mus.25666 |
container_title |
Muscle & Nerve |
container_volume |
57 |
container_issue |
2 |
container_start_page |
217 |
op_container_end_page |
221 |
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1810441252661886976 |