A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation
Abstract To evaluate pallidal DBS in a non‐DYT1 form of hereditary dystonia. We present the results of pallidal DBS in a family with non‐DYT1 dystonia where DYT5 to 17 was excluded. The dystonia is following an autosomal dominant pattern. Ten members had definite dystonia and five had dystonia with...
Published in: | Movement Disorders |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2009
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1002/mds.22842 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmds.22842 https://onlinelibrary.wiley.com/doi/full/10.1002/mds.22842 |
id |
crwiley:10.1002/mds.22842 |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1002/mds.22842 2024-06-02T08:12:10+00:00 A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation Blomstedt, Patric Hariz, Marwan I. Tisch, Stephen Holmberg, Monica Bergenheim, Tommy A. Forsgren, Lars 2009 http://dx.doi.org/10.1002/mds.22842 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmds.22842 https://onlinelibrary.wiley.com/doi/full/10.1002/mds.22842 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Movement Disorders volume 24, issue 16, page 2415-2419 ISSN 0885-3185 1531-8257 journal-article 2009 crwiley https://doi.org/10.1002/mds.22842 2024-05-03T11:53:19Z Abstract To evaluate pallidal DBS in a non‐DYT1 form of hereditary dystonia. We present the results of pallidal DBS in a family with non‐DYT1 dystonia where DYT5 to 17 was excluded. The dystonia is following an autosomal dominant pattern. Ten members had definite dystonia and five had dystonia with minor symptoms. Four patients received bilateral pallidal DBS. Mean age was 47 years. The patients were evaluated before surgery, and “on” stimulation after a mean of 2.5 years (range 1–3) using the Burke‐Fahn‐Marsden scale (BFM). Mean BFM score decreased by 79 % on stimulation, from 42.5 ± 24 to 9 ± 6.5 at the last evaluation. Cervical involvement improved by 89%. The 2 patients with oromandibular dystonia and blepharospasm demonstrated a reduction of 95% regarding these symptoms. The present study confirms the effectiveness of pallidal DBS in a new family with hereditary primary segmental and generalized dystonia. © 2009 Movement Disorder Society Article in Journal/Newspaper Northern Sweden Wiley Online Library Marsden ENVELOPE(66.067,66.067,-67.867,-67.867) Movement Disorders NA NA |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Abstract To evaluate pallidal DBS in a non‐DYT1 form of hereditary dystonia. We present the results of pallidal DBS in a family with non‐DYT1 dystonia where DYT5 to 17 was excluded. The dystonia is following an autosomal dominant pattern. Ten members had definite dystonia and five had dystonia with minor symptoms. Four patients received bilateral pallidal DBS. Mean age was 47 years. The patients were evaluated before surgery, and “on” stimulation after a mean of 2.5 years (range 1–3) using the Burke‐Fahn‐Marsden scale (BFM). Mean BFM score decreased by 79 % on stimulation, from 42.5 ± 24 to 9 ± 6.5 at the last evaluation. Cervical involvement improved by 89%. The 2 patients with oromandibular dystonia and blepharospasm demonstrated a reduction of 95% regarding these symptoms. The present study confirms the effectiveness of pallidal DBS in a new family with hereditary primary segmental and generalized dystonia. © 2009 Movement Disorder Society |
format |
Article in Journal/Newspaper |
author |
Blomstedt, Patric Hariz, Marwan I. Tisch, Stephen Holmberg, Monica Bergenheim, Tommy A. Forsgren, Lars |
spellingShingle |
Blomstedt, Patric Hariz, Marwan I. Tisch, Stephen Holmberg, Monica Bergenheim, Tommy A. Forsgren, Lars A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation |
author_facet |
Blomstedt, Patric Hariz, Marwan I. Tisch, Stephen Holmberg, Monica Bergenheim, Tommy A. Forsgren, Lars |
author_sort |
Blomstedt, Patric |
title |
A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation |
title_short |
A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation |
title_full |
A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation |
title_fullStr |
A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation |
title_full_unstemmed |
A family with a hereditary form of torsion dystonia from Northern Sweden treated with bilateral pallidal deep brain stimulation |
title_sort |
family with a hereditary form of torsion dystonia from northern sweden treated with bilateral pallidal deep brain stimulation |
publisher |
Wiley |
publishDate |
2009 |
url |
http://dx.doi.org/10.1002/mds.22842 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmds.22842 https://onlinelibrary.wiley.com/doi/full/10.1002/mds.22842 |
long_lat |
ENVELOPE(66.067,66.067,-67.867,-67.867) |
geographic |
Marsden |
geographic_facet |
Marsden |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
Movement Disorders volume 24, issue 16, page 2415-2419 ISSN 0885-3185 1531-8257 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/mds.22842 |
container_title |
Movement Disorders |
container_start_page |
NA |
op_container_end_page |
NA |
_version_ |
1800758525556686848 |