Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study
Abstract The bioavailability of long‐chain omega‐3 polyunsaturated fatty acids (n3 PUFA) can be affected by the form in which they are bound. An alternative source of n3 PUFA is Calanus finmarchicus oil (CO), which, unlike fish oil (FO) and krill oil (KO), contains fatty acids primarily bound as wax...
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crwiley:10.1002/lipd.12369 2024-09-15T18:00:42+00:00 Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study Vosskötter, Franziska Burhop, Milena Hahn, Andreas Schuchardt, Jan Philipp 2023 http://dx.doi.org/10.1002/lipd.12369 https://onlinelibrary.wiley.com/doi/pdf/10.1002/lipd.12369 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/lipd.12369 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Lipids volume 58, issue 3, page 129-138 ISSN 0024-4201 1558-9307 journal-article 2023 crwiley https://doi.org/10.1002/lipd.12369 2024-08-27T04:26:01Z Abstract The bioavailability of long‐chain omega‐3 polyunsaturated fatty acids (n3 PUFA) can be affected by the form in which they are bound. An alternative source of n3 PUFA is Calanus finmarchicus oil (CO), which, unlike fish oil (FO) and krill oil (KO), contains fatty acids primarily bound as wax esters. Recent studies have shown that n3 PUFA from CO are bioavailable to humans, but CO has not been compared to other marine oils such as FO or KO. Therefore, the aim of this study was to investigate the influence of 12 weeks supplementation with CO, FO and KO on the long‐term n3 PUFA status in healthy volunteers. The Omega‐3 Index (O3I), defined as red blood cell EPA + DHA content as a percentage of total identified fatty acids, was used as a measure to assess n3 PUFA status. Sixty‐two participants (mean ± standard deviation [SD] age: 29.7 ± 8.43 years) completed the randomized parallel group study (CO group: n = 21, 4 capsules/day, EPA + DHA dose: 242 mg/day; FO group: n = 22, 1 capsule/day, EPA + DHA dose: 248 mg/day; KO group: n = 19, 2 capsules/day, EPA + DHA dose: 286 mg/day). At baseline, the three groups showed comparable (mean ± SD) O3I values (CO: 5.13 ± 1.12%, FO: 4.90 ± 0.57%, KO: 4.87 ± 0.77%). The post‐interventional (mean ± SD) O3I increase was comparable between the three groups (CO: 1.09 ± 0.55%; FO: 1.0 ± 0.53%; KO: 1.15 ± 0.65%, all p < 0.001). The study confirms that CO can increase the n3 PUFA status comparable to FO and KO and is therefore an alternative marine source of bioavailable n3 PUFA, especially with regard to sustainability. Article in Journal/Newspaper Calanus finmarchicus Wiley Online Library Lipids 58 3 129 138 |
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Wiley Online Library |
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English |
description |
Abstract The bioavailability of long‐chain omega‐3 polyunsaturated fatty acids (n3 PUFA) can be affected by the form in which they are bound. An alternative source of n3 PUFA is Calanus finmarchicus oil (CO), which, unlike fish oil (FO) and krill oil (KO), contains fatty acids primarily bound as wax esters. Recent studies have shown that n3 PUFA from CO are bioavailable to humans, but CO has not been compared to other marine oils such as FO or KO. Therefore, the aim of this study was to investigate the influence of 12 weeks supplementation with CO, FO and KO on the long‐term n3 PUFA status in healthy volunteers. The Omega‐3 Index (O3I), defined as red blood cell EPA + DHA content as a percentage of total identified fatty acids, was used as a measure to assess n3 PUFA status. Sixty‐two participants (mean ± standard deviation [SD] age: 29.7 ± 8.43 years) completed the randomized parallel group study (CO group: n = 21, 4 capsules/day, EPA + DHA dose: 242 mg/day; FO group: n = 22, 1 capsule/day, EPA + DHA dose: 248 mg/day; KO group: n = 19, 2 capsules/day, EPA + DHA dose: 286 mg/day). At baseline, the three groups showed comparable (mean ± SD) O3I values (CO: 5.13 ± 1.12%, FO: 4.90 ± 0.57%, KO: 4.87 ± 0.77%). The post‐interventional (mean ± SD) O3I increase was comparable between the three groups (CO: 1.09 ± 0.55%; FO: 1.0 ± 0.53%; KO: 1.15 ± 0.65%, all p < 0.001). The study confirms that CO can increase the n3 PUFA status comparable to FO and KO and is therefore an alternative marine source of bioavailable n3 PUFA, especially with regard to sustainability. |
format |
Article in Journal/Newspaper |
author |
Vosskötter, Franziska Burhop, Milena Hahn, Andreas Schuchardt, Jan Philipp |
spellingShingle |
Vosskötter, Franziska Burhop, Milena Hahn, Andreas Schuchardt, Jan Philipp Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study |
author_facet |
Vosskötter, Franziska Burhop, Milena Hahn, Andreas Schuchardt, Jan Philipp |
author_sort |
Vosskötter, Franziska |
title |
Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study |
title_short |
Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study |
title_full |
Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study |
title_fullStr |
Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study |
title_full_unstemmed |
Equal bioavailability of omega‐3 PUFA from Calanus oil, fish oil and krill oil: A 12‐week randomized parallel study |
title_sort |
equal bioavailability of omega‐3 pufa from calanus oil, fish oil and krill oil: a 12‐week randomized parallel study |
publisher |
Wiley |
publishDate |
2023 |
url |
http://dx.doi.org/10.1002/lipd.12369 https://onlinelibrary.wiley.com/doi/pdf/10.1002/lipd.12369 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/lipd.12369 |
genre |
Calanus finmarchicus |
genre_facet |
Calanus finmarchicus |
op_source |
Lipids volume 58, issue 3, page 129-138 ISSN 0024-4201 1558-9307 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1002/lipd.12369 |
container_title |
Lipids |
container_volume |
58 |
container_issue |
3 |
container_start_page |
129 |
op_container_end_page |
138 |
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1810437872765894656 |