Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma
Abstract Greenland Eskimos comprise an ethnic group with one of the highest recorded incidence rates for nasopharyngeal carcinoma in the world. Sera from 625 Eskimos and 73 Danes (Caucasians) living in Greenland, as well as from 62 Danes living in Denmark, were tested for complement‐fixing antibody...
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crwiley:10.1002/ijc.2910290307 2024-06-02T08:06:07+00:00 Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma Levine, Paul H. Connelly, Roger R. Mestre, Miguel Ebbesen, Peter Das, Saroj Middleton, Moses 1982 http://dx.doi.org/10.1002/ijc.2910290307 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fijc.2910290307 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.2910290307 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor International Journal of Cancer volume 29, issue 3, page 265-268 ISSN 0020-7136 1097-0215 journal-article 1982 crwiley https://doi.org/10.1002/ijc.2910290307 2024-05-03T11:24:31Z Abstract Greenland Eskimos comprise an ethnic group with one of the highest recorded incidence rates for nasopharyngeal carcinoma in the world. Sera from 625 Eskimos and 73 Danes (Caucasians) living in Greenland, as well as from 62 Danes living in Denmark, were tested for complement‐fixing antibody to Epstein‐Barr virus (EBV) soluble antigen and, from this study group, 129 donors were matched by age and sex for a study comparing antibody to viral capsid antigen, early antigen, and soluble antigen. Both Eskimos and Danes living in Greenland had significantly higher titers of EBV antibodies than Danes living in Denmark, suggesting that environment was more important than genetics or socio‐economic factors in determining the antibody response to EBV. Age and sex were also factors, higher titers occurring in females and young Eskimos. Article in Journal/Newspaper eskimo* Greenland Wiley Online Library Greenland International Journal of Cancer 29 3 265 268 |
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Open Polar |
collection |
Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract Greenland Eskimos comprise an ethnic group with one of the highest recorded incidence rates for nasopharyngeal carcinoma in the world. Sera from 625 Eskimos and 73 Danes (Caucasians) living in Greenland, as well as from 62 Danes living in Denmark, were tested for complement‐fixing antibody to Epstein‐Barr virus (EBV) soluble antigen and, from this study group, 129 donors were matched by age and sex for a study comparing antibody to viral capsid antigen, early antigen, and soluble antigen. Both Eskimos and Danes living in Greenland had significantly higher titers of EBV antibodies than Danes living in Denmark, suggesting that environment was more important than genetics or socio‐economic factors in determining the antibody response to EBV. Age and sex were also factors, higher titers occurring in females and young Eskimos. |
format |
Article in Journal/Newspaper |
author |
Levine, Paul H. Connelly, Roger R. Mestre, Miguel Ebbesen, Peter Das, Saroj Middleton, Moses |
spellingShingle |
Levine, Paul H. Connelly, Roger R. Mestre, Miguel Ebbesen, Peter Das, Saroj Middleton, Moses Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
author_facet |
Levine, Paul H. Connelly, Roger R. Mestre, Miguel Ebbesen, Peter Das, Saroj Middleton, Moses |
author_sort |
Levine, Paul H. |
title |
Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
title_short |
Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
title_full |
Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
title_fullStr |
Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
title_full_unstemmed |
Complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
title_sort |
complement‐fixing antibody to epstein‐barr virus soluble antigen in populations at high and low risk for nasopharyngeal carcinoma |
publisher |
Wiley |
publishDate |
1982 |
url |
http://dx.doi.org/10.1002/ijc.2910290307 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fijc.2910290307 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.2910290307 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
eskimo* Greenland |
genre_facet |
eskimo* Greenland |
op_source |
International Journal of Cancer volume 29, issue 3, page 265-268 ISSN 0020-7136 1097-0215 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/ijc.2910290307 |
container_title |
International Journal of Cancer |
container_volume |
29 |
container_issue |
3 |
container_start_page |
265 |
op_container_end_page |
268 |
_version_ |
1800751006153179136 |