A PILOT BETA‐CAROTENE INTERVENTION TRIAL WITH INUITS USING SMOKELESS TOBACCO

• Published in: International Journal of Cancer
• Main Authors: STICH, Hans F., HORNBY, A. Paul, DUNN, Bruce P.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1985
• Subjects: Canada; Gjoa Haven; Northwest Territories; inuits
• Online Access: http://dx.doi.org/10.1002/ijc.1985.36.3.321; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fijc.1985.36.3.321; https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.1985.36.3.321

The frequency of exfoliated cells with micronuclei (MNC) was used to estimate the genotoxic effect of smokeless tobacco (snuff) on the oral mucosa and to follow the response to the administration of beta‐carotene (180 mg/week, given twice weekly in 6 capsules of 30 mg each). The pilot trial was carr...