Hematological reactions in the inhabitants of the Arctic on a polar night and a polar day

• Published in: Immunity, Inflammation and Disease
• Main Authors: Balashova, Svetlana N., Samodova, Anna V., Dobrodeeva, Liliya K., Belisheva, Natalya K.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2020
• Subjects: Arctic; Kola Peninsula; kola peninsula; polar night
• Online Access: http://dx.doi.org/10.1002/iid3.323; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fiid3.323; https://onlinelibrary.wiley.com/doi/pdf/10.1002/iid3.323; https://onlinelibrary.wiley.com/doi/full-xml/10.1002/iid3.323

Abstract Purpose The purpose of this study is to identify the features of hematological reactions in the inhabitants of the Arctic territory of the Kola Peninsula on a polar night and a polar day. Methods The study included determining the hemogram, neutrograms, monocytograms, lymphocytograms, and phagocytic activity neutrophil granulocytes, enzyme immunoassay, flow cytometry. Results It was established that during the polar night, there is an increase in the activity of migration of leukocytes from the marginal pool to the circulating pool, an increase in the intensity of phagocytosis by neutrophils, an increase in the concentrations of noradrenaline, cortisol, as well as an increase in hyperergic reactions involving immunoglobulin E and inhibitory processes due to an increase in interleukin‐10. Conclusion A prolonged lack of sunlight causes a decrease in the reserve capacity for regulating homeostasis and forces the body to use proliferative reactions, which is reflected in the increase in stab neutrophils, large lymphocytes in the structure of the lymphocytogram and CD10+ lymphocytes. In winters, the frequency of neutropenia registration also increases to 13% of cases, the deficit of phagocytic activity of neutrophils; lymphopenia is recorded in 20% with T‐helper deficiency (37%). A part of the population probably has a relatively high degree of vulnerability to the action of natural environmental factors and is not able to completely restore the initial levels of the effectiveness of adaptation reactions in the summer. So at the end of the polar day in 8% of adults born in the north, neutropenia is recorded and in 21%—lymphopenia.