The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA
Abstract In July 2000, 330 individuals of three flatfish species were collected from reference locations and nine sites surrounding the outfall of the Orange County (CA, USA) Sanitation District (OCSD) municipal wastewater discharge. Species included hornyhead turbot ( Pleuronichthys verticalis ), E...
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crwiley:10.1002/etc.5620220618 2024-06-23T07:57:20+00:00 The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA Roy, Luke A. Armstrong, Jeffrey L. Sakamoto, Ken Steinert, Scott Perkins, Edwin Lomax, Daniel P. Johnson, Lyndal L. Schlenk, Daniel 2003 http://dx.doi.org/10.1002/etc.5620220618 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fetc.5620220618 https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5620220618 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Environmental Toxicology and Chemistry volume 22, issue 6, page 1309-1317 ISSN 0730-7268 1552-8618 journal-article 2003 crwiley https://doi.org/10.1002/etc.5620220618 2024-06-11T04:44:46Z Abstract In July 2000, 330 individuals of three flatfish species were collected from reference locations and nine sites surrounding the outfall of the Orange County (CA, USA) Sanitation District (OCSD) municipal wastewater discharge. Species included hornyhead turbot ( Pleuronichthys verticalis ), English sole ( Pleuronectes vetulus ), and bigmouth sole ( Hippoglossina stomata ). Livers of sampled animals were examined for the expression of vitellogenin (in males), cytochrome P450 1A (CYP1A), and DNA damage (comet assay). Biliary fluorescent aromatic compounds (FACs) were also measured. Comparisons with tissue and sediment contaminant residues, liver histopathology, and population estimates were assessed to determine whether relationships exist between levels of biological organization. The CYP1A results indicated exposure to planar aromatic hydrocarbons at one nearshore site. Regression analysis of all English sole CYP1A to total sediment polychlorinated biphenyls (PCBs) ( r 2 = 0.97; p < 0.05) indicated a significant correlation. Widespread exposure to estrogens was observed at all sites without correlation to the abundance of the three species examined. Fluorescent aromatic compounds demonstrated no correlation to CYP1A expression. Overall, histopathology and biochemical endpoints did not indicate significant adverse effects in fish at the OCSD outfall. Article in Journal/Newspaper Turbot Wiley Online Library Environmental Toxicology and Chemistry 22 6 1309 1317 |
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English |
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Abstract In July 2000, 330 individuals of three flatfish species were collected from reference locations and nine sites surrounding the outfall of the Orange County (CA, USA) Sanitation District (OCSD) municipal wastewater discharge. Species included hornyhead turbot ( Pleuronichthys verticalis ), English sole ( Pleuronectes vetulus ), and bigmouth sole ( Hippoglossina stomata ). Livers of sampled animals were examined for the expression of vitellogenin (in males), cytochrome P450 1A (CYP1A), and DNA damage (comet assay). Biliary fluorescent aromatic compounds (FACs) were also measured. Comparisons with tissue and sediment contaminant residues, liver histopathology, and population estimates were assessed to determine whether relationships exist between levels of biological organization. The CYP1A results indicated exposure to planar aromatic hydrocarbons at one nearshore site. Regression analysis of all English sole CYP1A to total sediment polychlorinated biphenyls (PCBs) ( r 2 = 0.97; p < 0.05) indicated a significant correlation. Widespread exposure to estrogens was observed at all sites without correlation to the abundance of the three species examined. Fluorescent aromatic compounds demonstrated no correlation to CYP1A expression. Overall, histopathology and biochemical endpoints did not indicate significant adverse effects in fish at the OCSD outfall. |
format |
Article in Journal/Newspaper |
author |
Roy, Luke A. Armstrong, Jeffrey L. Sakamoto, Ken Steinert, Scott Perkins, Edwin Lomax, Daniel P. Johnson, Lyndal L. Schlenk, Daniel |
spellingShingle |
Roy, Luke A. Armstrong, Jeffrey L. Sakamoto, Ken Steinert, Scott Perkins, Edwin Lomax, Daniel P. Johnson, Lyndal L. Schlenk, Daniel The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA |
author_facet |
Roy, Luke A. Armstrong, Jeffrey L. Sakamoto, Ken Steinert, Scott Perkins, Edwin Lomax, Daniel P. Johnson, Lyndal L. Schlenk, Daniel |
author_sort |
Roy, Luke A. |
title |
The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA |
title_short |
The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA |
title_full |
The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA |
title_fullStr |
The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA |
title_full_unstemmed |
The relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of Orange County, California, USA |
title_sort |
relationships of biochemical endpoints to histopathology and population metrics in feral flatfish species collected near the municipal wastewater outfall of orange county, california, usa |
publisher |
Wiley |
publishDate |
2003 |
url |
http://dx.doi.org/10.1002/etc.5620220618 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fetc.5620220618 https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5620220618 |
genre |
Turbot |
genre_facet |
Turbot |
op_source |
Environmental Toxicology and Chemistry volume 22, issue 6, page 1309-1317 ISSN 0730-7268 1552-8618 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/etc.5620220618 |
container_title |
Environmental Toxicology and Chemistry |
container_volume |
22 |
container_issue |
6 |
container_start_page |
1309 |
op_container_end_page |
1317 |
_version_ |
1802650923031330816 |