Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey
Abstract Samples of sediment and eel taken from six sites in Amsterdam with different levels of water pollution were analyzed for 16 parental PAHs In addition, biliary PAH metabolites and hepatic PAH‐DNA adducts were determined in the eel to evaluate biomomtoring techniques for PAH exposure There wa...
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crwiley:10.1002/etc.5620130604 2024-06-02T07:55:11+00:00 Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey van der Oost, Ron Heida, Henk Satumalay, Karel van Schooten, Frederik‐Jan Ariese, Freek Vermeulen, Nico P. E. 1994 http://dx.doi.org/10.1002/etc.5620130604 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fetc.5620130604 https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5620130604 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Environmental Toxicology and Chemistry volume 13, issue 6, page 859-870 ISSN 0730-7268 1552-8618 journal-article 1994 crwiley https://doi.org/10.1002/etc.5620130604 2024-05-03T11:36:56Z Abstract Samples of sediment and eel taken from six sites in Amsterdam with different levels of water pollution were analyzed for 16 parental PAHs In addition, biliary PAH metabolites and hepatic PAH‐DNA adducts were determined in the eel to evaluate biomomtoring techniques for PAH exposure There was a clear difference between PAH profiles in sediments and eel Mainly two‐ and three‐ring PAHs were detected in eel, whereas four‐ring PAHs predominated in the sediments Because PAH bioaccumulation was highest in eel from the reference sites, tissue levels of the parental PAH are probably not the most accurate monitor of PAH exposure in fish An elevated excretion of 1 OH pyrene (determined by synchronous scan fluores cence) was observed in the bile of fish from three of the four polluted sites, indicating that this parameter may be used as a biomarker for PAH exposure A significant increase in PAH‐DNA adduct levels (determined by 32 P postlabeling) was observed in the liver of eel from all polluted sites Therefore, this parameter seems to be a sensitive biomarker for exposure to mutagenic and carcinogenic PAHs Article in Journal/Newspaper Anguilla anguilla Wiley Online Library Environmental Toxicology and Chemistry 13 6 859 870 |
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Open Polar |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract Samples of sediment and eel taken from six sites in Amsterdam with different levels of water pollution were analyzed for 16 parental PAHs In addition, biliary PAH metabolites and hepatic PAH‐DNA adducts were determined in the eel to evaluate biomomtoring techniques for PAH exposure There was a clear difference between PAH profiles in sediments and eel Mainly two‐ and three‐ring PAHs were detected in eel, whereas four‐ring PAHs predominated in the sediments Because PAH bioaccumulation was highest in eel from the reference sites, tissue levels of the parental PAH are probably not the most accurate monitor of PAH exposure in fish An elevated excretion of 1 OH pyrene (determined by synchronous scan fluores cence) was observed in the bile of fish from three of the four polluted sites, indicating that this parameter may be used as a biomarker for PAH exposure A significant increase in PAH‐DNA adduct levels (determined by 32 P postlabeling) was observed in the liver of eel from all polluted sites Therefore, this parameter seems to be a sensitive biomarker for exposure to mutagenic and carcinogenic PAHs |
format |
Article in Journal/Newspaper |
author |
van der Oost, Ron Heida, Henk Satumalay, Karel van Schooten, Frederik‐Jan Ariese, Freek Vermeulen, Nico P. E. |
spellingShingle |
van der Oost, Ron Heida, Henk Satumalay, Karel van Schooten, Frederik‐Jan Ariese, Freek Vermeulen, Nico P. E. Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey |
author_facet |
van der Oost, Ron Heida, Henk Satumalay, Karel van Schooten, Frederik‐Jan Ariese, Freek Vermeulen, Nico P. E. |
author_sort |
van der Oost, Ron |
title |
Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey |
title_short |
Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey |
title_full |
Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey |
title_fullStr |
Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey |
title_full_unstemmed |
Bioaccumulation, biotransformation and DNA binding of pahs in feral eel ( Anguilla anguilla) exposed to polluted sediments: A field survey |
title_sort |
bioaccumulation, biotransformation and dna binding of pahs in feral eel ( anguilla anguilla) exposed to polluted sediments: a field survey |
publisher |
Wiley |
publishDate |
1994 |
url |
http://dx.doi.org/10.1002/etc.5620130604 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fetc.5620130604 https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5620130604 |
genre |
Anguilla anguilla |
genre_facet |
Anguilla anguilla |
op_source |
Environmental Toxicology and Chemistry volume 13, issue 6, page 859-870 ISSN 0730-7268 1552-8618 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/etc.5620130604 |
container_title |
Environmental Toxicology and Chemistry |
container_volume |
13 |
container_issue |
6 |
container_start_page |
859 |
op_container_end_page |
870 |
_version_ |
1800746737967562752 |