Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling
Abstract Polycyclic aromatic hydrocarbons (PAHs) impaired pre‐migratory fueling in 49 orally dosed Sanderling ( Calidris alba ). In the present study, 8 genes related to fat deposition and PAH exposure were measured in liver subsamples from these same shorebirds. At the highest dose (1260 µg total P...
Published in: | Environmental Toxicology and Chemistry |
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crwiley:10.1002/etc.5056 2024-06-02T08:04:44+00:00 Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling Bianchini, Kristin Crump, Doug Farhat, Amani Morrissey, Christy A. University of Saskatchewan Natural Sciences and Engineering Research Council of Canada 2021 http://dx.doi.org/10.1002/etc.5056 https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5056 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/etc.5056 https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5056 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Environmental Toxicology and Chemistry volume 40, issue 7, page 1981-1989 ISSN 0730-7268 1552-8618 journal-article 2021 crwiley https://doi.org/10.1002/etc.5056 2024-05-03T10:56:37Z Abstract Polycyclic aromatic hydrocarbons (PAHs) impaired pre‐migratory fueling in 49 orally dosed Sanderling ( Calidris alba ). In the present study, 8 genes related to fat deposition and PAH exposure were measured in liver subsamples from these same shorebirds. At the highest dose (1260 µg total PAH [tPAH]/kg body wt/day), PAH exposure decreased liver basic fatty acid binding protein 1 ( Lbfabp ) and hepatic lipase ( Lipc ) expression. The present study reveals candidate molecular‐level pathways for observed avian pre‐migratory refueling impairment. Environ Toxicol Chem 2021;40:1981–1989. © 2021 SETAC Article in Journal/Newspaper Calidris alba Sanderling Wiley Online Library Environmental Toxicology and Chemistry 40 7 1983 1991 |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract Polycyclic aromatic hydrocarbons (PAHs) impaired pre‐migratory fueling in 49 orally dosed Sanderling ( Calidris alba ). In the present study, 8 genes related to fat deposition and PAH exposure were measured in liver subsamples from these same shorebirds. At the highest dose (1260 µg total PAH [tPAH]/kg body wt/day), PAH exposure decreased liver basic fatty acid binding protein 1 ( Lbfabp ) and hepatic lipase ( Lipc ) expression. The present study reveals candidate molecular‐level pathways for observed avian pre‐migratory refueling impairment. Environ Toxicol Chem 2021;40:1981–1989. © 2021 SETAC |
author2 |
University of Saskatchewan Natural Sciences and Engineering Research Council of Canada |
format |
Article in Journal/Newspaper |
author |
Bianchini, Kristin Crump, Doug Farhat, Amani Morrissey, Christy A. |
spellingShingle |
Bianchini, Kristin Crump, Doug Farhat, Amani Morrissey, Christy A. Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling |
author_facet |
Bianchini, Kristin Crump, Doug Farhat, Amani Morrissey, Christy A. |
author_sort |
Bianchini, Kristin |
title |
Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling |
title_short |
Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling |
title_full |
Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling |
title_fullStr |
Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling |
title_full_unstemmed |
Polycyclic Aromatic Hydrocarbons Alter the Hepatic Expression of Genes Involved in Sanderling ( Calidris alba) Pre‐migratory Fueling |
title_sort |
polycyclic aromatic hydrocarbons alter the hepatic expression of genes involved in sanderling ( calidris alba) pre‐migratory fueling |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1002/etc.5056 https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5056 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/etc.5056 https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.5056 |
genre |
Calidris alba Sanderling |
genre_facet |
Calidris alba Sanderling |
op_source |
Environmental Toxicology and Chemistry volume 40, issue 7, page 1981-1989 ISSN 0730-7268 1552-8618 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1002/etc.5056 |
container_title |
Environmental Toxicology and Chemistry |
container_volume |
40 |
container_issue |
7 |
container_start_page |
1983 |
op_container_end_page |
1991 |
_version_ |
1800749373778296832 |