DNA damage in Arctic seabirds: Baseline, sensitivity to a genotoxic stressor, and association with organohalogen contaminants

• Published in: Environmental Toxicology and Chemistry
• Main Authors: Haarr, Ane, Hylland, Ketil, Eckbo, Norith, Gabrielsen, Geir Wing, Herzke, Dorte, Bustnes, Jan Ove, Blévin, Pierre, Chastel, Olivier, Moe, Børge, Hanssen, Sveinn Are, Sagerup, Kjetil, Borgå, Katrine
• Other Authors: Research Council of Norway through Arctic Field, AVITOX, POLAR ECOTOX, Fram Centre flagship Hazardous Substances-Effects on Ecosystems and Human Health
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2018
• Subjects: Arctic; Norway; Svalbard; Arctic skua; Black guillemot; Black-legged Kittiwake; Cepphus grylle; Common Eider; Glaucous Gull; Great skua; Kongsfjord*; Kongsfjorden; Larus hyperboreus; rissa tridactyla; Somateria mollissima; Stercorarius parasiticus; Stercorarius skua
• Online Access: http://dx.doi.org/10.1002/etc.4035; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fetc.4035; https://setac.onlinelibrary.wiley.com/doi/pdf/10.1002/etc.4035

Abstract Environmental contaminants are found throughout Arctic marine ecosystems, and their presence in seabirds has been associated with toxicological responses. However, there are few studies of genotoxicity in Arctic avian wildlife. The purpose of the present study was to quantify deoxyribonucleic acid (DNA) damage in lymphocytes of selected seabird species and to examine whether accumulation of organohalogen contaminants (ΣOHCs) affects DNA damage. Blood was sampled from common eider ( Somateria mollissima ), black guillemot ( Cepphus grylle ), black‐legged kittiwake ( Rissa tridactyla ), glaucous gull ( Larus hyperboreus ), arctic skua ( Stercorarius parasiticus ), and great skua ( Stercorarius skua ) in Kongsfjorden, Svalbard (Norway). Contaminant concentrations found in the 6 species differed, presumably because of foraging ecology and biomagnification. Despite large differences in contaminant concentrations, ranging from ΣOHCs 3.3 ng/g wet weight in the common eider to ΣOHCs 895 ng/g wet weight in the great skua, there was no strong difference among the species in baseline DNA damage or sensitivity to a genotoxic stressor (hydrogen peroxide). Baseline levels of DNA damage were low, with median values ranging from 1.7% in the common eider to 8.6% in the great skua. There were no associations between DNA damage and contaminants in the investigated species, suggesting that contaminant concentrations in Kongsfjorden are too low to evoke genotoxic effects, or possibly that lymphocytes are resistant to strand breakage. Clearly, genotoxicity is a topic for future studies of Arctic seabirds. Environ Toxicol Chem 2018;37:1084–1091. © 2017 SETAC